公开(公告)号：US20240261399A1

公开(公告)日：2024-08-08

申请号：US18364431

申请日：2023-08-02

Applicant: Genentech, Inc.

Inventor： Ariel LOPEZ-CHAVEZ ,  Daniel Antonius WATERKAMP

IPC: A61K39/395 ,  A61K9/00 ,  A61K31/365 ,  A61K33/243 ,  A61K39/00 ,  A61P35/00

CPC classification number: A61K39/3955 ,  A61K9/0019 ,  A61K31/365 ,  A61K33/243 ,  A61P35/00 ,  A61K2039/505

Abstract: The present disclosure provides methods for treating lung cancer (such as small cell lung cancer, e.g., extensive stage small cell lung cancer) in an individual. The methods comprise administering to the individual a PD-1 axis binding antagonist (such as an anti-PD-L1 antibody, e.g., atezolizumab), a platinum agent (e.g., cisplatin or carboplatin), and a topoisomerase II inhibitor (e.g., etoposide).