公开(公告)号：US20230416403A1

公开(公告)日：2023-12-28

申请号：US18062473

申请日：2022-12-06

Applicant: Genmab A/S

Inventor： Sandra VERPLOEGEN ,  David P. E. SATIJN ,  Rene M. A. HOET ,  Paul PARREN ,  Jan VAN DE WINKEL ,  Vibeke Miller BREINHOLT ,  Eva EHRNROOTH ,  Ole BAADSGAARD ,  Tom VINK ,  Willem Karel BLEEKER ,  Mischa HOUTKAMP ,  Maroeska OUDSHOORN ,  Rob N. DE JONG

IPC: C07K16/36 ,  A61K39/395

CPC classification number: C07K16/36 ,  A61K39/395 ,  C07K2317/565 ,  A61K2039/505

Abstract: Isolated human monoclonal antibodies which bind to human TF and related antibody-based compositions and molecules, are disclosed. Also disclosed are pharmaceutical compositions comprising the antibodies, and therapeutic and diagnostic methods for using the antibodies.