公开(公告)号：US20240343741A1

公开(公告)日：2024-10-17

申请号：US18583002

申请日：2024-02-21

Applicant: H. Lundbeck A/S

Inventor： Thomas Jensen ,  Thomas Andersen ,  Mikkel Jessing ,  Jacob Nielsen ,  Henrik Daver ,  Christopher Richard Jones

IPC: C07D498/22

CPC classification number: C07D498/22 ,  C07B2200/05

Abstract: The present invention is directed to compounds of formula IIa




These compounds are considered useful for the treatment of diseases associated with leucine-rich repeat kinase 2 (LRRK2) such as Parkinson's disease. Furthermore, the invention relates to pharmaceutical compositions comprising said compounds.

公开(公告)号：US11958865B1

公开(公告)日：2024-04-16

申请号：US18467162

申请日：2023-09-14

Applicant: H. Lundbeck A/S

Inventor： Thomas Jensen ,  Thomas Andersen ,  Mikkel Jessing ,  Jacob Nielsen ,  Henrik Daver ,  Christopher Richard Jones

IPC: C07D498/22

CPC classification number: C07D498/22 ,  C07B2200/05 ,  C07D498/22 ,  C07B2200/05

Abstract: The present invention is directed to compounds of formula IIa




These compounds are considered useful for the treatment of diseases associated with leucine-rich repeat kinase 2 (LRRK2) such as Parkinson's disease. Furthermore, the invention relates to pharmaceutical compositions comprising said compounds.