公开(公告)号：US20220031676A1

公开(公告)日：2022-02-03

申请号：US17296489

申请日：2019-11-26

Applicant: H. Lundbeck A/S

Inventor： Channing Rodney BEALS ,  Dallas JONES ,  Jason Robert CLAPPER ,  Gary Paul O'NEILL ,  Iain Peter FRASER ,  Jacqueline Lorayne BLANKMAN ,  John J.M. WIENER ,  Cheryl A. GRICE

IPC: A61K31/438 ,  A61K31/496 ,  A61K31/5386 ,  A61K31/506

Abstract: Provided herein are methods for the treatment of disease with monoacylglycerol lipase (MAGL) inhibitors.

公开(公告)号：US20210230145A1

公开(公告)日：2021-07-29

申请号：US17227072

申请日：2021-04-09

Applicant: H. Lundbeck A/S

Inventor： Jacqueline Lorayne BLANKMAN ,  Jason Robert CLAPPER ,  R. Alan B. EZEKOWITZ ,  Iain Peter FRASER ,  Cheryl A. GRICE ,  Todd K. JONES ,  Gary Paul O'NEILL ,  Archie Wayne THURSTON, JR. ,  Channing Rodney BEALS

IPC: C07D403/10 ,  A61K31/495 ,  C07D295/205 ,  A61P29/00

Abstract: Provided herein are methods of treating inflammation or neuropathic pain using an effective dose of a monoacylglycerol lipase inhibitor or a composition thereof.