公开(公告)号：US11142517B2

公开(公告)日：2021-10-12

申请号：US16349142

申请日：2017-11-15

Applicant: H. Lundbeck A/S

Inventor： Cheryl A. Grice ,  Todd K. Jones ,  Kurt G. Grimm ,  Jacqueline Lorayne Blankman ,  Channing Rodney Beals

IPC: C07D403/10

Abstract: Described herein is the MAGL inhibitor 1,1,1,3,3,3-hexafluoropropan-2-yl 4-(2-(pyrrolidin-1-yl)-4-(trifluoromethyl)benzyl)piperazine-1-carboxylate, including crystalline forms and pharmaceutically acceptable salts and solvates thereof.

公开(公告)号：US11993588B2

公开(公告)日：2024-05-28

申请号：US17469535

申请日：2021-09-08

Applicant: H. Lundbeck A/S

Inventor： Cheryl A. Grice ,  Todd K. Jones ,  Kurt G. Grimm ,  Jacqueline Lorayne Blankman ,  Channing Rodney Beals

IPC: C07D403/10

CPC classification number: C07D403/10 ,  C07B2200/13

Abstract: Described herein is the MAGL inhibitor 1,1,1,3,3,3-hexafluoropropan-2-yl 4-(2-(pyrrolidin-1-yl)-4-(trifluoromethyl)benzyl)piperazine-1-carboxylate, including crystalline forms and pharmaceutically acceptable salts and solvates thereof.