公开(公告)号：US3915984A

公开(公告)日：1975-10-28

申请号：US42286173

申请日：1973-12-07

Applicant: HOECHST AG

Inventor： GEBERT ULRICH ,  BABEJ MILOS ,  GRANZER ERNOLD

IPC: C07D233/60 ,  C07D235/06 ,  C07D521/00

CPC classification number: C07D235/06 ,  C07D231/12 ,  C07D233/56 ,  C07D249/08

Abstract: Compounds of the formula

IN WHICH R1 and R2 each stands for a hydrogen atom or together they stand for the group -CH CH-CH CH- which may carry one or more lower alkyl, halogeno-alkyl or alkoxy groups, halogen atoms or NO2-groups, and R3 and R4, independently of one another, each stands for a hydrogen atom, a lower alkyl, halogeno-alkyl, alkoxy or halogeno-alkoxy group, a halogen atom or NO2 or together they stand as a -CH CH-CH CH- group with the benzene nucleus for the naphthyl group, AND PHYSIOLOGICALLY ACCEPTABLE ACID ADDITION SALTS THEREOF, PROCESS FOR PREPARING THEM AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AS ACTIVE SUBSTANCE.

Abstract translation: 式Ⅰ的化合物，其中R 1和R 2各自代表氢原子，或一起代表基团-CH = CH-CH = CH-，其可以携带一个或多个低级烷基，卤代烷基或烷氧基，卤素原子或 NO 2 - 基，R 3和R 4彼此独立地表示氢原子，低级烷基，卤代 - 烷基，烷氧基或卤代 - 烷氧基，卤素原子或NO 2，或者一起表示-CH = CH-CH = CH-基团与萘基的萘基，以及生理学上可接受的酸加法盐，其制备它们和作为活性物质的药物组合物的方法。