公开(公告)号：US20200268686A1

公开(公告)日：2020-08-27

申请号：US16871467

申请日：2020-05-11

Applicant: Harbins Ruhr Bioscience, Inc.

Inventor： Erich Gulbins ,  Karl Sebastian Lang ,  Judith Bezgovsek

IPC: A61K31/131 ,  A61P31/16 ,  A61K9/00

Abstract: Provided are processes for the prevention or treatment of viral infection in a subject. Some aspects provide administration of a sphingoid compound, optionally sphingosine, an active ingredient that activates generation of a sphingoid base, optionally of sphingosine; or an active agent that inhibits the degradation of a sphingoid base, optionally of sphingosine, to a subject such as a human. By increasing the local concentration of sphingosine in a subject or an area of a subject to which the composition is administered such as the nose or interior of the nose or portion thereof, the ability of viruses to infect the subject or cells thereof is reduced thereby treating of preventing infection by the virus.

公开(公告)号：US10688065B2

公开(公告)日：2020-06-23

申请号：US16588361

申请日：2019-09-30

Applicant: Harbins Ruhr Bioscience, Inc.

Inventor： Erich Gulbins ,  Karl Sebastian Lang ,  Judith Bezgovsek

IPC: A61K31/131 ,  A61P31/16 ,  A61K9/00

Abstract: Provided are processes for the prevention or treatment of viral infection in a subject. Some aspects provide administration of a sphingoid compound, optionally sphingosine, an active ingredient that activates generation of a sphingoid base, optionally of sphingosine; or an active agent that inhibits the degradation of a sphingoid base, optionally of sphingosine, to a subject such as a human. By increasing the local concentration of sphingosine in a subject or an area of a subject to which the composition is administered such as the nose or interior of the nose or portion thereof, the ability of viruses to infect the subject or cells thereof is reduced thereby treating of preventing infection by the virus.

公开(公告)号：US12083079B2

公开(公告)日：2024-09-10

申请号：US16871467

申请日：2020-05-11

Applicant: Harbins Ruhr Bioscience, Inc.

Inventor： Erich Gulbins ,  Karl Sebastian Lang ,  Judith Bezgovsek

IPC: A61K31/131 ,  A61K9/00 ,  A61P31/16

CPC classification number: A61K31/131 ,  A61K9/0019 ,  A61P31/16 ,  A61K9/0043 ,  C12Y305/01023 ,  C12Y305/01109

Abstract: Provided are processes for the prevention or treatment of viral infection in a subject. Some aspects provide administration of a sphingoid compound, optionally sphingosine, an active ingredient that activates generation of a sphingoid base, optionally of sphingosine; or an active agent that inhibits the degradation of a sphingoid base, optionally of sphingosine, to a subject such as a human. By increasing the local concentration of sphingosine in a subject or an area of a subject to which the composition is administered such as the nose or interior of the nose or portion thereof, the ability of viruses to infect the subject or cells thereof is reduced thereby treating of preventing infection by the virus.

公开(公告)号：US20200113850A1

公开(公告)日：2020-04-16

申请号：US16588361

申请日：2019-09-30

Applicant: Harbins Ruhr Bioscience, Inc.

Inventor： Erich Gulbins ,  Karl Sebastian Lang ,  Judith Bezgovsek

IPC: A61K31/131 ,  A61P31/16 ,  A61K9/00

Abstract: Provided are processes for the prevention or treatment of viral infection in a subject. Some aspects provide administration of a sphingoid compound, optionally sphingosine, an active ingredient that activates generation of a sphingoid base, optionally of sphingosine; or an active agent that inhibits the degradation of a sphingoid base, optionally of sphingosine, to a subject such as a human. By increasing the local concentration of sphingosine in a subject or an area of a subject to which the composition is administered such as the nose or interior of the nose or portion thereof, the ability of viruses to infect the subject or cells thereof is reduced thereby treating of preventing infection by the virus.