专利检索 ap:("JONGWON LIM" OR "MICHAEL D. ALTMAN" OR "MATTHEW L. CHILDERS" OR "CRAIG R. GIBEAU" OR "GINNY DAI HO" OR "HONCHUNG TSUI" OR "MERCK SHARP & DOHME CORP.") AND inv:"HONCHUNG TSUI" 第 1 页

1.

发明申请
CARBOXAMIDE INHIBITORS OF IRAK4 ACTIVITY 审中-公开

公开(公告)号：US20180051027A1

公开(公告)日：2018-02-22

申请号：US15557195

申请日：2016-03-07

申请人： JONGWON LIM , MICHAEL D. ALTMAN , MATTHEW L. CHILDERS , CRAIG R. GIBEAU , GINNY DAI HO , HONCHUNG TSUI , MERCK SHARP & DOHME CORP.

发明人： JONGWON LIM , MICHAEL D. ALTMAN , MATTHEW L. CHILDERS , CRAIG R. GIBEAU , GINNY DAI HO , HONCHUNG TSUI

IPC分类号： C07D487/04 , A61K45/06 , A61K31/519 , A61K31/5377 , A61K31/635 , C07D495/04 , A61K31/4985 , A61K31/53

CPC分类号： C07D487/04 , A61K31/4985 , A61K31/519 , A61K31/53 , A61K31/5377 , A61K31/635 , A61K45/06 , C07D495/04

摘要： The present invention relates to carboxamide inhibitors of IRAK4 of formula (I) and provides compositions comprising such inhibitors, as well as methods therewith for treating IRAK4-mediated or -associated conditions or diseases.