公开(公告)号：US20100290016A1

公开(公告)日：2010-11-18

申请号：US12811532

申请日：2009-01-02

申请人： Bryan Kaehr ,  Rex Nielson ,  Jason B. Shear

发明人： Bryan Kaehr ,  Rex Nielson ,  Jason B. Shear

IPC分类号： G03B27/68 ,  G03B27/32

CPC分类号： G03F7/70416 ,  B29C64/129 ,  G03F7/70291 ,  G03F7/703 ,  G03F7/70375

摘要： According to certain embodiments, systems comprising an energy source; at least one conjugate mask; a magnification device; and a fabrication material; wherein the at least one conjugate mask is disposed between the energy source and the magnification device; and wherein the fabrication material is disposed operable to the magnification device. According to other embodiments, methods and composition employing such systems.

摘要翻译： 根据某些实施例，包括能量源的系统; 至少一个共轭掩模; 放大装置; 和制造材料; 其中所述至少一个共轭掩模设置在所述能量源和所述放大装置之间; 并且其中所述制造材料设置成可操作于所述放大装置。 根据其他实施例，采用这种系统的方法和组合。

公开(公告)号：US20090035745A1

公开(公告)日：2009-02-05

申请号：US12185184

申请日：2008-08-04

申请人： Jason B. Shear ,  Rex Nielson

发明人： Jason B. Shear ,  Rex Nielson

IPC分类号： C12Q3/00 ,  C12M3/00

CPC分类号： C12M29/04 ,  C12M23/34

摘要： Systems and methods for site-specific dosing of cellular cultures are provided. Some of the systems provided comprise at least two laminar flow channels; and an ablatable membrane that is disposed between the at least two laminar flow channels. Other systems provided comprise at least two laminar flow channels; and an ablated membrane that is disposed between the at least two laminar flow channels. Some of the methods provided comprise providing at least two laminar flow channels; providing a membrane disposed between the at least two laminar flow channels, wherein the membrane is selected from the group consisting of an ablatable membrane and an ablated membrane; placing cells into at least one of the at least two laminar flow channels; providing a reagent medium; and flowing the reagent medium through at least one other of the at least two laminar flow channels.

摘要翻译： 提供了用于细胞培养物的特异性定量给药的系统和方法。 提供的一些系统包括至少两个层流通道; 以及布置在所述至少两个层流通道之间的可烧烤膜。 提供的其它系统包括至少两个层流通道; 以及设置在所述至少两个层流通道之间的消融膜。 提供的一些方法包括提供至少两个层流通道; 提供设置在所述至少两个层流通道之间的膜，其中所述膜选自可消融膜和消融膜; 将细胞置于所述至少两个层流通道中的至少一个中; 提供试剂介质; 并且使所述试剂介质流过所述至少两个层流通道中的至少另一个。