公开(公告)号：US10711049B2

公开(公告)日：2020-07-14

申请号：US15553191

申请日：2016-06-21

Applicant: KOREA INSTITUTE OF INDUSTRIAL TECHNOLOGY

Inventor： Woo-Jong Lee ,  Sung-Gun Kim ,  Dong-Mok Lee ,  Hee-Kyung An ,  Chi-Min Choi

IPC: C07K14/47 ,  C07K14/705 ,  C07K19/00 ,  C12N15/63 ,  G01N33/53 ,  G01N33/538 ,  C12N15/62

Abstract: The present disclosure relates to a method for producing a TLR5 agonist protein. According to the present disclosure, the TLR5 agonist protein can be easily separated and purified after biotechnological production. In particular, the fusion partner used for separation and purification is effectively removed so as to minimize the possibility of inhibiting binding to TLR5 and inducing an immune response by the fusion partner.

公开(公告)号：US10041032B2

公开(公告)日：2018-08-07

申请号：US14891149

申请日：2014-06-26

Applicant: KOREA INSTITUTE OF INDUSTRIAL TECHNOLOGY

Inventor： Woo-Jong Lee

IPC: C12M1/12 ,  C12M1/00

Abstract: The present invention relates to a simple animal cell culture device and a method for culturing animal cells using the same, and provides a simple animal cell culture device comprising: a culture vessel for holding a culture medium; an animal cell reservoir coupled to the upper portion of the culture vessel; a cell support housed on the inside of the animal cell reservoir and having animal cells adhered thereto; and a cover for covering the top of the culture vessel.