公开(公告)号：US20250163223A1

公开(公告)日：2025-05-22

申请号：US19019853

申请日：2025-01-14

Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY

Inventor： Soo Chang SONG ,  Ki Hyun HONG

IPC: C08G79/025 ,  A61K9/50 ,  A61K38/04 ,  A61K45/06 ,  C08J3/075 ,  C08J3/20 ,  C08J3/24

Abstract: Provided is a hydrogel composition including thermosensitive poly(phosphazene) to which a plurality of hydrophobic amino acids, hydrophilic polymers, and host molecules are substituted; and a physiologically active material linked to a guest molecule, wherein the poly(phosphazene) and the physiologically active material form a conjugate by inclusion of the guest molecule in the host molecule via a host-guest interaction.

公开(公告)号：US20210009763A1

公开(公告)日：2021-01-14

申请号：US16906028

申请日：2020-06-19

Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY

Inventor： Soo Chang SONG ,  Ki Hyun HONG

IPC: C08G79/025 ,  C08J3/075 ,  C08J3/20 ,  C08J3/24 ,  A61K38/04 ,  A61K9/50

Abstract: Provided is a hydrogel composition including thermosensitive poly(phosphazene) to which a plurality of hydrophobic amino acids, hydrophilic polymers, and host molecules are substituted; and a physiologically active material linked to a guest molecule, wherein the poly(phosphazene) and the physiologically active material form a conjugate by inclusion of the guest molecule in the host molecule via a host-guest interaction.