公开(公告)号：US20220162206A1

公开(公告)日：2022-05-26

申请号：US17440879

申请日：2020-03-30

Applicant: KOWA COMPANY, LTD.

Inventor： Gen WATANABE ,  Toshiharu MORIMOTO ,  Akira IWATA ,  Hirotaka SASAKI ,  Takahisa OGAMINO ,  Kosuke USUDA ,  Ayumu OKUDA ,  Hiroyuki ISHIWATA ,  Yuichiro TABUNOKI ,  Keigo NISHII

IPC: C07D471/04 ,  C07D519/00

Abstract: To provide a novel compound or a salt thereof or a solvate thereof, having a CSF-1R inhibitory activity and exhibiting antitumor effect.
An azaindole derivative of formula (I): wherein A represents a C6-10 aryl ring, an aromatic heterocycle, or an unsaturated heterocycle, and A optionally has one substituent or more same or different substituents; and R represents a C1-3 alkyl group or a saturated heterocyclic group, or a salt thereof or a solvate thereof.