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公开(公告)号:US20090318788A1
公开(公告)日:2009-12-24
申请号:US12109836
申请日:2008-04-25
申请人: Kalle LEVON , Miriam RAFAILOVICH , Basil RIGAS , Yantian Wang
发明人: Kalle LEVON , Miriam RAFAILOVICH , Basil RIGAS , Yantian Wang
IPC分类号: A61B5/1468
CPC分类号: G01N33/5438 , B82Y15/00 , B82Y30/00 , C12Q1/003 , G01N2610/00
摘要: The present invention relates to combining surface molecular imprinting (SMI) with the production of self-assembled monolayers (SAM) of hydroxyl alkanethiolate molecules on gold coated chip surfaces. In this technique, the sensing element is placed on the transducer and the whole assembly can then be miniaturized and integrated into a smart chip. These sensors can detect, nanomolar quantities of complex biomolecules.
摘要翻译: 本发明涉及将表面分子印迹(SMI)与在金涂覆的芯片表面上生产羟基链烷硫醇盐分子的自组装单层(SAM)。 在这种技术中,感测元件放置在换能器上,然后可以将整个组件小型化并集成到智能芯片中。 这些传感器可以检测纳摩尔量的复合生物分子。
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公开(公告)号:US20130225529A1
公开(公告)日:2013-08-29
申请号:US13779382
申请日:2013-02-27
申请人: Basil RIGAS
发明人: Basil RIGAS
IPC分类号: A61K31/661 , A61K45/06 , A61K31/192 , A61K31/675 , A61K31/664
CPC分类号: A61K31/661 , A61K31/166 , A61K31/167 , A61K31/192 , A61K31/216 , A61K31/4985 , A61K31/6615 , A61K31/664 , A61K31/665 , A61K31/675 , A61K31/683 , A61K45/06
摘要: Phospho-ester compounds and pharmaceutical compositions thereof administered by the respiratory and other routes for the prevention and/or treatment of lung and brain cancer and precancerous conditions thereof, for the treatment of pain, for the treatment of skin disorders, for treating and/or preventing inflammation-related diseases, and for the treatment and prevention of cancer.
摘要翻译: 磷酸酯化合物及其药物组合物,其通过呼吸道和其它途径施用以预防和/或治疗肺癌和脑癌及其癌前病症,用于治疗疼痛,用于治疗皮肤病症,用于治疗和/或 预防炎症相关疾病,以及治疗和预防癌症。
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公开(公告)号:US20120316139A1
公开(公告)日:2012-12-13
申请号:US13559884
申请日:2012-07-27
申请人: Basil RIGAS
发明人: Basil RIGAS
IPC分类号: A61K31/661 , C07F9/6574 , A61K31/6615 , A61P29/00 , A61P9/00 , A61P25/28 , A61P25/00 , A61P37/00 , A61P35/00 , A61P9/12 , A61P19/04 , A61P11/08 , A61P11/02 , A61P35/02 , C07F9/09
CPC分类号: A61K31/6615 , A61K31/661 , C07F9/091 , C07F9/093 , C07F9/094 , C07F9/65742
摘要: Compounds of the general formula are disclosed with activity towards treating diseases related to inflammation, such as cancer, neurodegenerative and cardiovascular diseases. Pharmaceutical compositions and methods of use are also disclosed.
摘要翻译: 公开了通式的化合物,其具有治疗与炎症相关疾病如癌症,神经变性和心血管疾病的活性。 还公开了药物组合物和使用方法。
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