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Patent Agency Ranking
公开(公告)号：US10451635B2
公开(公告)日：2019-10-22
申请号：US15339773
申请日：2016-10-31
Applicant: Korea Basic Science Institute
Inventor： Ik Soon Jang , Jong Soon Choi , Joseph Kwon , Dong-Gi Lee , Kyeong Eun Yang
Abstract: The present invention relates to a beef-specific age determination marker containing the p21 protein, to an antibody specifically bound to bovine p21 protein, to a beef-specific age determination kit containing the antibody which is specifically bound to the bovine p21 protein, and to a method which involves detecting the bovine p21 protein through an antigen-antibody binding reaction using the antibody which is specifically bound to the bovine p21 protein serving as a beef-specific age determination marker in the muscle tissue of beef, so as to determine the age of the beef. According to the present invention, the p21 protein is significantly greatly expressed in the muscle tissue of beef, the age of which is lower than 30 months, and is hardly expressed in the muscle tissue of beef, the age of which is greater than 30 months, and thus can be valuably used as a beef-specific age determination marker.
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公开(公告)号：US20160090640A1
公开(公告)日：2016-03-31
申请号：US14499801
申请日：2014-09-29
Inventor： Joseph Kwon , Jong-Soon Choi , Duwoon Kim , Hee-Min Lee
CPC classification number: C12Q1/701 , C12N7/02 , C12N2770/16011 , C12N2770/32411 , C12Q1/706 , Y02A50/54
Abstract: Disclosed is an economic method for concentrating virus and detecting virus, such that virus in a sample solution having low virus concentration can be concentrated with high efficiency within a short time. Particularly, the method comprising the steps of: (A) adding Concanavalin A (Con A) to a sample solution containing a virus, and reacting the added Concanavalin A with the virus in the sample solution to form a virus-Concanavalin A conjugate; and (B) separating the virus-Concanavalin A conjugate from the sample solution.
Abstract translation: 公开了一种用于浓缩病毒和检测病毒的经济方法，使得可以在短时间内以高效率浓缩具有低病毒浓度的样品溶液中的病毒。 特别地，该方法包括以下步骤：（A）将伴刀豆球蛋白A（Con A）加入到含有病毒的样品溶液中，并将加入的伴刀豆球蛋白A与病毒在样品溶液中反应，形成病毒 - 伴刀豆球蛋白A缀合物; 和（B）从样品溶液中分离病毒 - 伴刀豆球蛋白A缀合物。
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公开(公告)号：US10379108B2
公开(公告)日：2019-08-13
申请号：US15151180
申请日：2016-05-10
Inventor： Du Woon Kim , Joseph Kwon
IPC: G01N33/50 , C12Q1/68 , A61K38/16 , G01N33/569
Abstract: Discloses are a method for detecting Norovirus using a Norovirus animal model, a method for screening an antivial agent against Norovirus, and a composition for neutralizing the infection with an enteric virus, containing concanavalin A as an active ingredient, so that the method for detecting Norovirus can allow the distinction between infectious Norovirus and non-infectious Norovirus, and the composition can neutralize a virus causing food poisoning.
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公开(公告)号：US10094831B2
公开(公告)日：2018-10-09
申请号：US14584394
申请日：2014-12-29
Applicant: GWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY , KOREA BASIC SCIENCE INSTITUTE , INDUSTRY FOUNDATION OF CHONNAM NATIONAL UNIVERSITY
Inventor： Sung Yang , Du-Woon Kim , Joseph Kwon , Sung-A Hong , Jong-Soon Choi , Heemin Lee
IPC: G01N33/569 , G01N27/327 , G01N33/543
Abstract: Disclosed herein are a norovirus detection sensor and an electrochemical sensing method using the sensor. Specifically, in the norovirus detection sensor including a bioreceptor and a signal detector, a three-dimensional gold nanosurface electrode is used as a substrate, and the bioreceptor employs concanavalin A as a sample capture agent immobilized to the substrate and capable of binding to norovirus. Therefore, the norovirus detection sensor has improved sensitivity by employing the three-dimensional gold nanosurface electrode having a wide surface area. In addition, the norovirus detection sensor has effects of reducing manufacturing costs using a non-antibody material, i.e., concanavalin A which is inexpensive and readily available.
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公开(公告)号：US09322071B2
公开(公告)日：2016-04-26
申请号：US14499801
申请日：2014-09-29
Inventor： Joseph Kwon , Jong-Soon Choi , Duwoon Kim , Hee-Min Lee
CPC classification number: C12Q1/701 , C12N7/02 , C12N2770/16011 , C12N2770/32411 , C12Q1/706 , Y02A50/54
Abstract: Disclosed is an economic method for concentrating virus and detecting virus, such that virus in a sample solution having low virus concentration can be concentrated with high efficiency within a short time. Particularly, the method comprising the steps of: (A) adding Concanavalin A (Con A) to a sample solution containing a virus, and reacting the added Concanavalin A with the virus in the sample solution to form a virus-Concanavalin A conjugate; and (B) separating the virus-Concanavalin A conjugate from the sample solution.
Abstract translation: 公开了一种用于浓缩病毒和检测病毒的经济方法，使得可以在短时间内以高效率浓缩具有低病毒浓度的样品溶液中的病毒。 特别地，该方法包括以下步骤：（A）将伴刀豆球蛋白A（Con A）加入到含有病毒的样品溶液中，并将加入的伴刀豆球蛋白A与病毒在样品溶液中反应，形成病毒 - 伴刀豆球蛋白A缀合物; 和（B）从样品溶液中分离病毒 - 伴刀豆球蛋白A缀合物。
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