公开(公告)号：US20170143668A1

公开(公告)日：2017-05-25

申请号：US15415883

申请日：2017-01-26

Applicant: Macau University of Science and Technology

Inventor： Wen-zhe MA ,  Sen-ling FENG ,  Xiao-jun YAO ,  Zhong-wen YUAN ,  Liang LIU ,  Ying XIE

IPC: A61K31/366 ,  A61K31/704 ,  A61K31/337

CPC classification number: A61K31/366 ,  A61K31/337 ,  A61K31/352 ,  A61K31/704 ,  A61K45/06 ,  A61K2300/00

Abstract: The present invention discloses a pharmaceutical composition of treating multidrug resistance cancer, comprising a citrus methoxyflavone and a chemotherapeutic drug, in which the citrus methoxyflavone is nobiletin. A method of treating multidrug resistance cancer comprising administrating citrus methoxyflavone and a chemotherapeutic drug is also disclosed.

公开(公告)号：US20170027901A1

公开(公告)日：2017-02-02

申请号：US14848358

申请日：2015-09-09

Applicant: Macau University of Science and Technology

Inventor： Wen-zhe MA ,  Sen-ling FENG ,  Xiao-jun YAO ,  Zhong-wen YUAN ,  Liang LIU ,  Ying XIE

IPC: A61K31/353 ,  A61K31/704 ,  A61K31/337

CPC classification number: A61K31/366 ,  A61K31/337 ,  A61K31/352 ,  A61K31/704 ,  A61K45/06 ,  A61K2300/00

Abstract: The present invention discloses a pharmaceutical composition of treating multidrug resistance cancer, comprising a citrus methoxyflavone and a chemotherapeutic drug, in which the citrus methoxyflavone is nobiletin. A method of treating multidrug resistance cancer comprising administrating citrus methoxyflavone and a chemotherapeutic drug is also disclosed.

Abstract translation: 本发明公开了一种治疗多药耐药性的药物组合物，其包含柑橘类甲氧基黄酮和化学治疗药物，其中柑橘类甲氧基黄酮是诺贝利林。 还公开了一种治疗多药耐药性的方法，其包括施用柑橘甲氧基黄酮和化疗药物。

公开(公告)号：US20170027900A1

公开(公告)日：2017-02-02

申请号：US14848360

申请日：2015-09-09

Applicant: Macau University of Science and Technology

Inventor： Wen-zhe MA ,  Sen-ling FENG ,  Xiao-jun YAO ,  Zhong-wen YUAN ,  Liang LIU ,  Ying XIE

IPC: A61K31/352 ,  A61K31/704 ,  A61K31/337

CPC classification number: A61K31/352 ,  A61K31/337 ,  A61K31/704 ,  A61K45/06 ,  A61K2300/00

Abstract: The present invention discloses a pharmaceutical composition of treating multidrug resistance cancer, comprising a citrus methoxyflavone and a chemotherapeutic drug, in which the citrus methoxyflavone is tangeretin. A method of treating multidrug resistance cancer comprising administrating citrus methoxyflavone and a chemotherapeutic drug is also disclosed.

Abstract translation: 本发明公开了一种治疗多药耐药性的药物组合物，其包含柑橘类甲氧基黄酮和化学治疗药物，其中柑橘类甲氧基黄酮为甜菜碱。 还公开了一种治疗多药耐药性的方法，其包括施用柑橘甲氧基黄酮和化疗药物。