Method of producing 1,2,4-oxadiazole derivatives
    2.
    发明申请
    Method of producing 1,2,4-oxadiazole derivatives 失效
    制备1,2,4-恶二唑衍生物的方法

    公开(公告)号:US20080086009A1

    公开(公告)日:2008-04-10

    申请号:US11662280

    申请日:2006-04-06

    IPC分类号: C07D271/12

    CPC分类号: C07D271/06

    摘要: A method for producing a 1,2,4-oxadiazol derivative represented by the formula (1): (1) [wherein, R1 represents a methyl group or a phenyl group, and R2 represents an optionally substituted linear or branched alkyl group], which comprises reacting a nitrile represented by the formula (2): (2) [wherein, R2 represents an optionally substituted linear or branched alkyl group] with acetone or acetophenone in the presence of iron (III) nitrate. The method allows a 1,2,4-oxadiazol derivative exhibiting a useful biological activity to be produced in good yield without the discharge of a harmful waste.

    摘要翻译: 由式(1)表示的1,2,4-恶二唑衍生物的制造方法:(1)[式中,R 1表示甲基或苯基,R“ 2表示任选取代的直链或支链烷基],其包括使由式(2)表示的腈:(2)[其中,R 2表示任选取代的直链或支链烷基 支化烷基]与丙酮或苯乙酮在硝酸铁(III)存在下反应。 该方法允许以良好的产率生产显示出有用的生物活性的1,2,4-恶二唑衍生物而不排出有害废物。

    Apparatus for creating a turning program
    4.
    发明申请
    Apparatus for creating a turning program 有权
    用于创建车削程序的装置

    公开(公告)号:US20080086230A1

    公开(公告)日:2008-04-10

    申请号:US11902201

    申请日:2007-09-19

    IPC分类号: G06F19/00

    摘要: One element is taken from a machined shape. When the element is a straight line element, whether or not the distance D between the start point and the end point of the element in a direction orthogonal to the axis of rotation of the workpiece is equal to or greater than a preset value Ds is determined. In addition, whether or not an angle A that the straight line element makes with the Z-axis is equal to or greater than a preset angle Aa is determined. When the distance D is equal to or greater than the preset value Ds and the angle A is equal to or greater than the preset angle Aa, a program is created with the cutting direction reversed from the profile direction.

    摘要翻译: 一个元素取自加工形状。 当元件是直线元件时,确定元件在与工件的旋转轴线正交的方向上的起始点和终点之间的距离D是否等于或大于预设值Ds 。 此外,确定直线元件与Z轴形成的角度A是否等于或大于预设角度Aa。 当距离D等于或大于预设值Ds并且角度A等于或大于预设角度Aa时,产生具有与轮廓方向相反的切割方向的程序。

    Apparatus for creating a turning program
    5.
    发明授权
    Apparatus for creating a turning program 有权
    用于创建车削程序的装置

    公开(公告)号:US07747336B2

    公开(公告)日:2010-06-29

    申请号:US11902201

    申请日:2007-09-19

    IPC分类号: G05B19/4093

    摘要: One element is taken from a machined shape. When the element is a straight line element, whether or not the distance D between the start point and the end point of the element in a direction orthogonal to the axis of rotation of the workpiece is equal to or greater than a preset value Ds is determined. In addition, whether or not an angle A that the straight line element makes with the Z-axis is equal to or greater than a preset angle Aa is determined. When the distance D is equal to or greater than the preset value Ds and the angle A is equal to or greater than the preset angle Aa, a program is created with the cutting direction reversed from the profile direction.

    摘要翻译: 一个元素取自加工形状。 当元件是直线元件时,确定元件在与工件的旋转轴线正交的方向上的起始点和终点之间的距离D是否等于或大于预设值Ds 。 此外,确定直线元件与Z轴形成的角度A是否等于或大于预设角度Aa。 当距离D等于或大于预设值Ds并且角度A等于或大于预设角度Aa时,产生具有与轮廓方向相反的切割方向的程序。

    Method of producing 1,2,4-oxadiazole derivatives
    6.
    发明授权
    Method of producing 1,2,4-oxadiazole derivatives 失效
    制备1,2,4-恶二唑衍生物的方法

    公开(公告)号:US07576220B2

    公开(公告)日:2009-08-18

    申请号:US11662280

    申请日:2006-04-06

    IPC分类号: C07D271/12

    CPC分类号: C07D271/06

    摘要: A method for producing a 1,2,4-oxadiazol derivative represented by the formula (1): (1) [wherein, R1 represents a methyl group or a phenyl group, and R2 represents an optionally substituted linear or branched alkyl group], which comprises reacting a nitrile represented by the formula (2): (2) [wherein, R2 represents an optionally substituted linear or branched alkyl group] with acetone or acetophenone in the presence of iron (III) nitrate. The method allows a 1,2,4-oxadiazol derivative exhibiting a useful biological activity to be produced in good yield without the discharge of a harmful waste.

    摘要翻译: 一种由式(1)表示的1,2,4-恶二唑衍生物的制造方法:(1)[式中,R1表示甲基或苯基,R2表示任意取代的直链或支链烷基] 其包括在硝酸铁(III)存在下,将由式(2)表示的腈:(2)[其中,R 2表示任选取代的直链或支链烷基]与丙酮或苯乙酮反应。 该方法允许以良好的产率生产显示出有用的生物活性的1,2,4-恶二唑衍生物而不排出有害废物。