公开(公告)号：US20130058952A1

公开(公告)日：2013-03-07

申请号：US13499429

申请日：2010-10-01

申请人： Michael Roggendorf ,  Anna-Maria Eis-Hübinger ,  Jürgen Krauss ,  Karl Eduard Schneweis ,  Edelgard Schneweis ,  Michaela Arndt ,  Adalbert Krawczyk ,  Evelyn Exner ,  Martin P. Däumer

发明人： Michael Roggendorf ,  Anna-Maria Eis-Hübinger ,  Jürgen Krauss ,  Karl Eduard Schneweis ,  Edelgard Schneweis ,  Michaela Arndt ,  Adalbert Krawczyk ,  Evelyn Exner ,  Martin P. Däumer

IPC分类号： A61K39/42 ,  A61P31/22 ,  C07K16/46 ,  C07K16/08

CPC分类号： C07K16/087 ,  A61K39/00 ,  A61K2039/505 ,  C07K2317/24 ,  C07K2317/34 ,  C07K2317/54 ,  C07K2317/55 ,  C07K2317/565 ,  C07K2317/567 ,  C07K2317/76 ,  C07K2317/92

摘要： The invention relates to an anti-HSV antibody as defined in the claims, a pharmaceutical composition comprising of an effective amount of the said antibody, an expression vector comprising of a nucleotide sequence which encodes the said antibody, a host cell comprising of the said nucleotide sequence, a hybridoma cell capable of producing the said antibody and the use of the said antibody as a drug, in particular to use for the manufacture of a drug for the prophylactical or therapeutical treatment of HSV-associated diseases in a subject; as defined in the claims.

公开(公告)号：US08889137B2

公开(公告)日：2014-11-18

申请号：US13499429

申请日：2010-10-01

申请人： Michael Roggendorf ,  Anna-Maria Eis-Hübinger ,  Jürgen Krauss ,  Karl Eduard Schneweis ,  Michaela Arndt ,  Adalbert Krawczyk ,  Evelyn Exner ,  Martin P. Däumer ,  Edelgard Schneweis

发明人： Michael Roggendorf ,  Anna-Maria Eis-Hübinger ,  Jürgen Krauss ,  Karl Eduard Schneweis ,  Michaela Arndt ,  Adalbert Krawczyk ,  Evelyn Exner ,  Martin P. Däumer

IPC分类号： A61K39/245 ,  C07K16/08 ,  A61K39/00

CPC分类号： C07K16/087 ,  A61K39/00 ,  A61K2039/505 ,  C07K2317/24 ,  C07K2317/34 ,  C07K2317/54 ,  C07K2317/55 ,  C07K2317/565 ,  C07K2317/567 ,  C07K2317/76 ,  C07K2317/92

摘要： The invention relates to an anti-HSV antibody as defined in the claims, a pharmaceutical composition comprising of an effective amount of the said antibody, an expression vector comprising of a nucleotide sequence which encodes the said antibody, a host cell comprising of the said nucleotide sequence, a hybridoma cell capable of producing the said antibody and the use of the said antibody as a drug, in particular to use for the manufacture of a drug for the prophylactical or therapeutical treatment of HSV-associated diseases in a subject; as defined in the claims.

摘要翻译： 本发明涉及权利要求中定义的抗HSV抗体，包含有效量的所述抗体的药物组合物，包含编码所述抗体的核苷酸序列的表达载体，包含所述核苷酸的宿主细胞 序列，能够产生所述抗体的杂交瘤细胞和所述抗体作为药物的用途，特别是用于制备用于预防或治疗性治疗受试者中HSV相关疾病的药物; 如权利要求中所限定。