公开(公告)号：US07074420B2

公开(公告)日：2006-07-11

申请号：US10288603

申请日：2002-11-05

申请人： Michele C. Duggan ,  Lorraine M. Cowton ,  John Duffy

发明人： Michele C. Duggan ,  Lorraine M. Cowton ,  John Duffy

IPC分类号： A61K7/00 ,  A61K7/42 ,  A61K7/44 ,  A61K7/021 ,  A61K7/025

CPC分类号： A61Q19/005 ,  A61K8/671 ,  A61Q19/08

摘要： There is provided a topical composition and method for improving the aesthetic appearance of skin, particularly, preventing, ameliorating, treating and/or reducing fine lines and/or wrinkles, without the skin irritation typically associated with topical application of a retinoid. There is also provided a topical composition and method for improving the aesthetic appearance of lips, particularly decreasing the number and/or depth of vertical lip lines. The composition has an effective amount of retinoxytrimethylsilane. Preferably, the composition is applied daily to skin and/or lips. The composition and method are particularly suitable for persons having sensitive skin.

公开(公告)号：US06299889B1

公开(公告)日：2001-10-09

申请号：US09150806

申请日：1998-09-10

申请人： Lorraine M. Cowton ,  John A. Duffy ,  Michele C. Duggan

发明人： Lorraine M. Cowton ,  John A. Duffy ,  Michele C. Duggan

IPC分类号： A61K600

CPC分类号： A61K8/345 ,  A61K8/19 ,  A61K8/20 ,  A61K8/27 ,  A61K8/37 ,  A61K8/676 ,  A61K31/375 ,  A61K45/06 ,  A61Q19/10 ,  Y10S514/844 ,  A61K2300/00

摘要： Stable cosmetic compositions containing high levels of ascorbic acid, relatively low levels of water, varying levels of polyhydric alcohol, and organic carbonate are disclosed. The compositions may also include monohydric alcohol or hydroxyalkyl cellulose or both. The compositions are homogeneous solutions, and can be adapted to be topically applied to the skin to impart appearance benefits thereto.

摘要翻译： 公开了含有高水平的抗坏血酸，相对低水平的水，不同含量的多元醇和有机碳酸盐的稳定的化妆品组合物。 组合物还可以包括一元醇或羟烷基纤维素或两者。 组合物是均匀溶液，并且可以适于局部施用于皮肤以赋予其外观有益效果。

公开(公告)号：US06641824B2

公开(公告)日：2003-11-04

申请号：US10039745

申请日：2001-11-09

申请人： Michele Duggan ,  Lorraine M. Cowton

发明人： Michele Duggan ,  Lorraine M. Cowton

IPC分类号： A61K700

CPC分类号： A61Q19/005 ,  A61K8/671 ,  A61Q19/08

摘要： There is provided a topical composition and method for improving the aesthetic appearance of skin, particularly, preventing, ameliorating, treating and/or reducing fine lines and/or wrinkles, without the skin irritation typically associated with topical application of a retinoid. The composition has an effective amount of retinoxytrimethylsilane. Preferably, the composition is applied daily to skin. The composition and method are particularly suitable for persons having sensitive skin.

摘要翻译： 提供了一种外用组合物和方法，其用于改善皮肤的美学外观，特别是防止，改善，治疗和/或减少细纹和/或皱纹，而没有通常与视黄酸酯的局部应用相关的皮肤刺激。 组合物具有有效量的视黄基三甲基硅烷。 优选地，将组合物每天施用于皮肤。 组合物和方法特别适合于具有敏感皮肤的人。