公开(公告)号：US10895571B2

公开(公告)日：2021-01-19

申请号：US14896182

申请日：2014-06-05

申请人： Minicare B.V.

发明人： Toon Hendrik Evers ,  Menno Willem Jose Prins ,  Jeroen Hans Nieuwenhuis

IPC分类号： G01N33/543 ,  G01N33/53

摘要： Methods for preventing aggregation of detection particles in a test for detecting a multi-epitope target analyte comprising two or more similar or identical epitopes in a sample and/or for determining the concentration of the multi-epitope target analyte in a sample by applying a first capture entity which can specifically bind to at least one epitope on the multi-epitope analyte and block the at least one epitope from binding to a detection particle. The detection of the multi-epitope target analyte may further include the use of a second capture entity, which can specifically bind to the same or a similar epitope of the multi-epitope target analyte as the first capture entity. The multi-epitope target may be detected through the use of a system comprising a sensor surface and the use of a first capture entity to block the at least one epitope from binding to a detection particle.

公开(公告)号：US10384153B2

公开(公告)日：2019-08-20

申请号：US14373131

申请日：2013-01-23

申请人： Minicare B.V.

发明人： Jacobus Hermanus Maria Neijzen ,  Toon Hendrik Evers

IPC分类号： B01D29/05 ,  B01D29/01 ,  B01L3/00

摘要： The invention relates to a filter unit (600), a method for manufacturing such a filter unit, and a cartridge (690) comprising such a filter unit. The filter unit (600) is characterized in that it comprises a filter material (601) which is integrated into the aperture of at least one foil (602, 603, 604). In a preferred embodiment, the filter material (601) may be located in the aperture of an intermediate foil (604) which is embedded between a top foil (602) and a bottom foil (603). Such a filter unit (600) can readily be produced in cost-effective processes like roll-to-roll manufacturing technologies.