公开(公告)号：US11427586B2

公开(公告)日：2022-08-30

申请号：US17101510

申请日：2020-11-23

Applicant: NOVARTIS AG

Inventor： Kelly D. Boss ,  Yi Fan ,  Alec Nathanson Flyer ,  Declan Hardy ,  Zhihong Huang ,  Kathryn Taylor Linkens ,  Jon Christopher Loren ,  Fupeng Ma ,  Valentina Molteni ,  Duncan Shaw ,  Jeffrey Smith ,  Catherine Fooks Solovay

IPC: C07D471/10 ,  C07D413/14 ,  C07D491/107 ,  C07D413/06 ,  A61P27/04

Abstract: Provided herein are compounds and pharmaceutical compositions useful for treating meibomian gland dysfunction (MGD), comprising administering to a subject in need thereof a therapeutically effective amount of a compound of Formula (I) or a compound of Formula (I′), or pharmaceutical composition described herein.