公开(公告)号：US11692046B2

公开(公告)日：2023-07-04

申请号：US17127600

申请日：2020-12-18

Applicant: Novartis AG

Inventor： Regis Cebe ,  Stephane Olland ,  David Langdon Yowe

IPC: C07K16/40 ,  C07K16/28 ,  A61K39/395 ,  A61K39/00

CPC classification number: C07K16/40 ,  A61K39/39591 ,  C07K16/2863 ,  A61K2039/505 ,  A61K2039/545 ,  C07K2317/24 ,  C07K2317/75 ,  C07K2317/92 ,  C07K2317/94

Abstract: The present disclosure relates to monoclonal antibodies and antigen-binding fragments thereof that bind to human β-klotho, and pharmaceutical compositions and methods of treatment comprising the same.

公开(公告)号：US20210171659A1

公开(公告)日：2021-06-10

申请号：US17127600

申请日：2020-12-18

Applicant: Novartis AG

Inventor： Regis Cebe ,  Stephane Olland ,  David Langdon Yowe

IPC: C07K16/40 ,  A61K39/395 ,  C07K16/28

Abstract: The present disclosure relates to monoclonal antibodies and antigen-binding fragments thereof that bind to human β-klotho, and pharmaceutical compositions and methods of treatment comprising the same.

公开(公告)号：US10899844B2

公开(公告)日：2021-01-26

申请号：US15890302

申请日：2018-02-06

Applicant: Novartis AG

Inventor： Regis Cebe ,  Stephane Olland ,  David Langdon Yowe

IPC: C07K16/40 ,  A61K39/395 ,  C07K16/28 ,  A61K39/00

Abstract: The present disclosure relates to monoclonal antibodies and antigen-binding fragments thereof that bind to human β-klotho, and pharmaceutical compositions and methods of treatment comprising the same.