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公开(公告)号:US20180125996A1
公开(公告)日:2018-05-10
申请号:US15690737
申请日:2017-08-30
Applicant: Novartis AG
Inventor: Tinya ABRAMS , Steven COHEN , Christie P. FANTON , Catrin FINNER , Thomas HUBER , Kathy MILLER , Siew Ho SCHLEYER , Kathrin Ulrike TISSOT-DAGUETTE
CPC classification number: A61K47/6803 , A61K9/0019 , A61K9/19 , A61K31/537 , A61K39/39591 , A61K45/06 , A61K47/12 , A61K47/26 , A61K47/6801 , A61K47/6849 , A61K47/6855 , A61K47/6857 , A61K47/6865 , A61K47/6867 , A61K47/6889 , A61K47/6921 , A61K49/00 , A61K51/103 , A61K51/1093 , A61K2039/505 , A61P35/00 , C07K16/2803 , C07K16/2863 , C07K16/32 , C07K2317/14 , C07K2317/21 , C07K2317/24 , C07K2317/30 , C07K2317/33 , C07K2317/34 , C07K2317/55 , C07K2317/565 , C07K2317/73 , C07K2317/732 , C07K2317/76 , C07K2317/77 , C07K2317/92 , G01N33/53 , G01N33/574 , G01N33/57492
Abstract: The present invention relates to anti-cKIT antibodies, antibody fragments, antibody drug conjugates, and their uses for the treatment of cancer.