公开(公告)号：US20120134921A1

公开(公告)日：2012-05-31

申请号：US13377692

申请日：2010-06-11

申请人： Oddveig Sellaeg Helland ,  Gry Stensrud ,  Bjorn Klem ,  Jon Erik Braenden ,  Aslak Godal ,  Jo Klavenes

发明人： Oddveig Sellaeg Helland ,  Gry Stensrud ,  Bjorn Klem ,  Jon Erik Braenden ,  Aslak Godal ,  Jo Klavenes

IPC分类号： A61K51/04 ,  A61K49/00

CPC分类号： A61K31/197 ,  A61K9/0009 ,  A61K9/4858 ,  A61K41/0061 ,  A61K49/0036

摘要： This invention relates to solid compositions and solid pharmaceutical products for use in methods of photodynamic diagnosis of cancer, pre-cancerous and non-cancerous conditions in the lower part of the gastrointestinal system. The solid pharmaceutical compositions and pharmaceutical products comprise an active ingredient which is 5-aminolevulinic acid (5-ALA) or a precursor or derivative of 5-ALA or pharmaceutically acceptable salts thereof. The invention relates further to methods of photodynamic diagnosis of cancer, pre-cancerous and non-cancerous conditions of the lower gastrointestinal tract, wherein the solid pharmaceutical compositions and pharmaceutical products are used.

摘要翻译： 本发明涉及用于癌症的光动力学诊断方法，胃肠系统下部癌前和非癌症病症的固体组合物和固体药物产品。 固体药物组合物和药物产品包含5-氨基乙酰丙酸（5-ALA）或5-ALA的前体或衍生物的活性成分或其药学上可接受的盐。 本发明还涉及癌症的光动力学诊断方法，下胃肠道的癌前和非癌症状况，其中使用固体药物组合物和药物产品。