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公开(公告)号:US10233178B2
公开(公告)日:2019-03-19
申请号:US15623866
申请日:2017-06-15
申请人: Oryzon Genomics S.A.
发明人: Alberto Ortega Muñoz , Matthew Colin Thor Fyfe , Marc Martinell Pedemonte , Iñigo Tirapu Fernandez De La Cuesta , Maria de los Ángeles Estiarte Martinez
IPC分类号: A61K31/505 , A61K31/44 , C07D417/12 , A61K31/433 , A61K31/4245 , A61K31/422 , A61K31/506 , A61K31/4439 , C07D213/73 , C07D237/20 , C07D239/42 , C07D241/20 , C07D253/07 , C07D261/14 , C07D263/48 , C07D271/07 , C07D271/113 , C07D277/40 , C07D285/12 , C07D401/12 , C07D413/12 , C07D285/135 , C07D285/08
摘要: The invention relates to (hetero)aryl cyclopropylamine compounds, including particularly the compounds of formula (I) as described and defined herein, and their use in therapy, including, e.g., in the treatment or prevention of cancer, a neurological disease or condition, or a viral infection. Thus, in one specific aspect the invention relates to formulas (II), (III), (IV), (V), (VI), (VII), (VIII), (IX).
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公开(公告)号:US09708309B2
公开(公告)日:2017-07-18
申请号:US14848649
申请日:2015-09-09
申请人: Oryzon Genomics S.A.
发明人: Alberto Ortega Muñoz , Matthew Colin Thor Fyfe , Marc Martinell Pedemonte , Iñigo Tirapu Fernandez De La Cuesta , Maria de los Ángeles Estiarte-Martinez
IPC分类号: C07D239/02 , C07D413/00 , C07D417/00 , A61K31/505 , A61K31/44 , C07D417/12 , A61K31/433 , A61K31/4245 , A61K31/422 , C07D213/73 , C07D237/20 , C07D239/42 , C07D241/20 , C07D253/07 , C07D261/14 , C07D263/48 , C07D271/07 , C07D271/113 , C07D277/40 , C07D285/12 , C07D401/12 , C07D413/12 , C07D285/135 , C07D285/08
CPC分类号: C07D417/12 , A61K31/422 , A61K31/4245 , A61K31/433 , C07D213/73 , C07D237/20 , C07D239/42 , C07D241/20 , C07D253/07 , C07D261/14 , C07D263/48 , C07D271/07 , C07D271/113 , C07D277/40 , C07D285/08 , C07D285/12 , C07D285/135 , C07D401/12 , C07D413/12
摘要: The invention relates to (hetero)aryl cyclopropylamine compounds, including particularly the compounds of formula (I) as described and defined herein, and their use in therapy, including, e.g., in the treatment or prevention of cancer, a neurological disease or condition, or a viral infection. Thus, in one specific aspect the invention relates to formulas (II), (III), (IV), (V), (VI), (VII), (VIII), (IX).
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