公开(公告)号：US20180010093A1

公开(公告)日：2018-01-11

申请号：US15542200

申请日：2016-01-13

Applicant: Osaka University

Inventor： Kohji Nishida ,  Ryuhei HAYASHI ,  Yuki ISHIKAWA

IPC: C12N5/079 ,  C12N5/074

CPC classification number: C12N5/0621 ,  C12N5/0607 ,  C12N5/10 ,  C12N2500/90 ,  C12N2501/117 ,  C12N2501/727 ,  C12N2506/45

Abstract: The present invention relates to a method for inducing the differentiation of corneal epithelial cells from pluripotent stem cells. More specifically, the present invention relates to a method for autonomously differentiating pluripotent stem cells, such as human iPS cells, into ectodermal cell lineage in a serum-free medium without using feeder cells and inducing the differentiation of the resultant ocular surface ectodermal lineage cells into corneal epithelial cells.

公开(公告)号：US20210371818A1

公开(公告)日：2021-12-02

申请号：US17348174

申请日：2021-06-15

Applicant: Osaka University

Inventor： Kohji NISHIDA ,  Ryuhei HAYASHI ,  Yuki ISHIKAWA

IPC: C12N5/079 ,  C12N5/10 ,  C12N5/074

Abstract: The present invention relates to a method for inducing the differentiation of corneal epithelial cells from pluripotent stem cells. More specifically, the present invention relates to a method for autonomously differentiating pluripotent stem cells, such as human iPS cells, into ectodermal cell lineage in a serum-free medium without using feeder cells and inducing the differentiation of the resultant ocular surface ectodermal lineage cells into corneal epithelial cells.