公开(公告)号：US20230263792A1

公开(公告)日：2023-08-24

申请号：US18006584

申请日：2021-07-30

Applicant: PHAROS IBIO CO., LTD ,  KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY

Inventor： Tae Bo SIM ,  Seung Hye CHOI ,  Han Na CHO ,  Woo Young HUR ,  Chi Man SONG ,  Ky Youb NAM ,  Jeong Hyeok YOON

IPC: A61K31/4535 ,  A61P35/02 ,  A61P29/00

CPC classification number: A61K31/4535 ,  A61P35/02 ,  A61P29/00

Abstract: The present invention relates to the use of a 2,3,5-substituted thiophene compound for the prevention, amelioration or treatment of mastocytosis. The 2,3,5-substituted thiophene compound has excellent inhibitory activity against the growth of mastocytosis cells and against an inflammatory response caused by mastocytosis, and thus may be effectively used for the prevention, amelioration or treatment of mastocytosis.

公开(公告)号：US20230270733A1

公开(公告)日：2023-08-31

申请号：US18006582

申请日：2021-07-30

Applicant: PHAROS IBIO CO., LTD. ,  KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY

Inventor： Tae Bo SIM ,  Seung Hye CHOI ,  Han Na CHO ,  Nam Kyoung KIM ,  Woo Young HUR ,  Chi Man SONG ,  Ky Youb NAM ,  Jeong Hyeok YOON

IPC: A61K31/4535 ,  A23L33/10 ,  A61P35/00

CPC classification number: A61K31/4535 ,  A23L33/10 ,  A61P35/00

Abstract: The present invention relates to the use of a 2,3,5-substituted thiophene compound for the prevention, amelioration or treatment of gastrointestinal stromal tumor. The 2,3,5-substituted thiophene compound exhibits high inhibitory activity against the growth of gastrointestinal stromal tumor, and thus may be effectively used for the prevention, amelioration or treatment of gastrointestinal stromal tumor.

公开(公告)号：US20230293507A1

公开(公告)日：2023-09-21

申请号：US17905510

申请日：2021-03-04

Applicant: PHAROS IBIO CO., LTD

Inventor： Jeong Hyeok YOON ,  Ky Youb NAM

IPC: A61K31/4535 ,  A61K33/243 ,  A61K31/337 ,  A61K31/4745 ,  A61K31/502 ,  A61P35/00

CPC classification number: A61K31/4535 ,  A61K33/243 ,  A61K31/337 ,  A61K31/4745 ,  A61K31/502 ,  A61P35/00

Abstract: The present invention relates to a composition for preventing, ameliorating, or treating ovarian cancer, the composition containing a 2,3,5-substituted thiophene compound. The composition has excellent inhibitory activity against the proliferation of ovarian cancer, and thus may be effectively used for preventing, ameliorating, or treating ovarian cancer.