Method for applying renewable polymeric lens coating
    3.
    发明授权
    Method for applying renewable polymeric lens coating 失效
    应用可再生聚合物镜片涂层的方法

    公开(公告)号:US06638563B2

    公开(公告)日:2003-10-28

    申请号:US10128172

    申请日:2002-04-22

    IPC分类号: C08J704

    摘要: The present invention is directed toward the renewable surface treatment of medical devices such as contact lenses and medical implants. In particular, the present invention is directed to a method of modifying the surface of a medical device to increase its biocompatibility or hydrophilicity by coating the device with a removable hydrophilic polymer by means of reaction between reactive functionalities on the hydrophilic polymer which functionalities are complementary to reactive functionalities on or near the surface of the medical device at reaction temperatures of less than about 55° C.

    摘要翻译: 本发明涉及医疗装置如隐形眼镜和医用植入物的可再生表面处理。 特别地,本发明涉及通过借助亲水性聚合物上的反应性官能团之间的反应涂覆具有可去除的亲水性聚合物的装置来改变医疗装置的表面以增加其生物相容性或亲水性的方法,其功能性与 在小于约55℃的反应温度下,医疗器械表面上或附近的反应性官能团

    Surface modification of functional group-containing medical devices with catalyst-containing reactive polymer system
    4.
    发明授权
    Surface modification of functional group-containing medical devices with catalyst-containing reactive polymer system 失效
    含有催化剂的反应性聚合物体系的含官能团医疗器械的表面改性

    公开(公告)号:US07270678B2

    公开(公告)日:2007-09-18

    申请号:US10187154

    申请日:2002-06-28

    IPC分类号: A61F2/16 A61F2/14

    摘要: Surface modified medical devices such as intraocular lens implants formed from one or more functional group-containing materials using reactive, hydrophilic polymers with catalyst functionality for the purpose of reducing or eliminating lens epithelial cell growth thereon, reducing or eliminating silicone oil absorption upon subsequent surgical exposure and/or reducing implantation inserter friction is provided herein. Additionally, a method of making and using surface modified intraocular lens implants is provided.

    摘要翻译: 使用具有催化剂官能团的反应性亲水性聚合物由一种或多种含官能团的材料形成的表面改性的医疗装置,例如用于减少或消除其上的镜片上皮细胞生长的目的,减少或消除随后手术暴露时的硅油吸收 和/或减少植入插入物摩擦。 另外,提供了制造和使用表面改性的眼内透镜植入物的方法。

    Surface treatment of medical device
    7.
    发明授权
    Surface treatment of medical device 有权
    医疗器械表面处理

    公开(公告)号:US06958169B2

    公开(公告)日:2005-10-25

    申请号:US10321949

    申请日:2002-12-17

    CPC分类号: A61L27/34 A61L27/50

    摘要: A method for improving the wettability of a medical device involves: (a) providing a medical device formed from a monomer mixture comprising a hydrophilic device-forming monomer including a copolymerizable group and an electron donating moiety, and a second device-forming monomer including a copolymerizable group and a reactive functional group; and (b) contacting a surface of the medical device with a wetting agent including a proton donating moiety reactive with the functional group provided by the second lens-forming monomer and that complexes with the electron donating moiety provided by the hydrophilic lens-forming monomer.

    摘要翻译: 一种用于改善医疗装置的润湿性的方法包括:(a)提供由包含包含可共聚基团和给电子部分的亲水装置形成单体的单体混合物形成的医疗装置,以及第二装置形成单体, 可共聚基团和反应性官能团; 和(b)使医疗装置的表面与包含与由第二透镜形成性单体提供的官能团反应的质子供体部分的润湿剂和与亲水性透镜形成性单体提供的给电子部分的配合物接触。