公开(公告)号：US20150266962A1

公开(公告)日：2015-09-24

申请号：US14439897

申请日：2013-10-30

Applicant: PFIZER INC.

Inventor： Dangshe Ma ,  Fang Jin ,  Lioudmila Gennadievna Tchistiakova ,  Puja Sapra

IPC: C07K16/28 ,  G01N33/574 ,  A61K47/48

CPC classification number: C07K16/2866 ,  A61K47/6803 ,  A61K47/6845 ,  A61K47/6849 ,  A61K47/6889 ,  A61K2039/505 ,  C07K2317/24 ,  C07K2317/33 ,  C07K2317/56 ,  C07K2317/565 ,  C07K2317/76 ,  C07K2317/77 ,  C07K2317/92 ,  C07K2317/94 ,  G01N33/57492 ,  G01N2333/7155

Abstract: Disclosed herein are anti-IL-13-Rα2 antibodies and antibody drug conjugates and methods for preparing and using the same.

Abstract translation: 本文公开了抗IL-13-Rα2抗体和抗体药物共轭物及其制备和使用方法。

公开(公告)号：US11434292B2

公开(公告)日：2022-09-06

申请号：US16417859

申请日：2019-05-21

Applicant: Pfizer Inc.

Inventor： James Reasoner Apgar ,  Fang Jin ,  Madan Katragadda ,  Divya Mathur ,  Lioudmila Gennadievna Tchistiakova

IPC: C07K16/28 ,  A61P35/00 ,  C07K16/30 ,  C07K16/40 ,  C07K16/46 ,  A61K39/00

Abstract: The present invention provides novel antibodies that specifically bind to CD3 and uses thereof. The invention also provides therapeutic and diagnostic methods utilizing the antibodies and antigen-binding fragments provided herein.

公开(公告)号：US09828428B2

公开(公告)日：2017-11-28

申请号：US14439897

申请日：2013-10-30

Applicant: Pfizer Inc.

Inventor： Dangshe Ma ,  Fang Jin ,  Lioudmila Gennadievna Tchistiakova ,  Puja Sapra

IPC: C07K16/28 ,  A61K47/48 ,  G01N33/574 ,  A61K39/395 ,  A61K39/00

CPC classification number: C07K16/2866 ,  A61K47/6803 ,  A61K47/6845 ,  A61K47/6849 ,  A61K47/6889 ,  A61K2039/505 ,  C07K2317/24 ,  C07K2317/33 ,  C07K2317/56 ,  C07K2317/565 ,  C07K2317/76 ,  C07K2317/77 ,  C07K2317/92 ,  C07K2317/94 ,  G01N33/57492 ,  G01N2333/7155

Abstract: Disclosed herein are anti-IL-13-Rα2 antibodies and antibody drug conjugates and methods for preparing and using the same.

公开(公告)号：US20190382486A1

公开(公告)日：2019-12-19

申请号：US16417859

申请日：2019-05-21

Applicant: Pfizer Inc.

Inventor： James Reasoner Apgar ,  Fang Jin ,  Madan Katragadda ,  Divya Mathur ,  Lioudmila Gennadievna Tchistiakova

IPC: C07K16/28 ,  C07K16/46 ,  C07K16/30 ,  C07K16/40 ,  A61P35/00

Abstract: The present invention provides novel antibodies that specifically bind to CD3 and uses thereof. The invention also provides therapeutic and diagnostic methods utilizing the antibodies and antigen-binding fragments provided herein.