公开(公告)号：US20250066337A1

公开(公告)日：2025-02-27

申请号：US18684225

申请日：2022-08-23

Applicant: Pfizer Inc.

Inventor： Kevin Francis DeBoyace ,  Brian Matthew Samas ,  Heather Lynn Frericks Schmidt

IPC: C07D405/14 ,  A61K31/506 ,  A61K45/06

Abstract: Solid forms of (S)-2-(5-((3-ethoxypyridin-2-yl)oxy)pyridin-3-yl)-N-(tetrahydrofuran-3-yl)pyrimidine-5-carboxamide, including crystalline forms and an amorphous form, in addition to pharmaceutical compositions, processes for preparing, and their use to treat diseases, conditions and disorders modulated by the activity of the diacylglycerol acyltransferase 2 (DGAT2) in a mammal such as a human are described herein.