公开(公告)号：US12138302B2

公开(公告)日：2024-11-12

申请号：US17509110

申请日：2021-10-25

Applicant: Pfizer Inc.

Inventor： Annaliesa Sybil Anderson ,  Laurent Oliver Chorro ,  Robert George Konrad Donald ,  Jacqueline Marie Lypowy ,  Rosalind Pan

IPC: A61K39/108 ,  A61K39/00 ,  A61P31/04 ,  A61P37/04

Abstract: This invention relates to compositions that include a polypeptide derived from E. coli or a fragment thereof; and modified O-polysaccharide molecules derived from E. coli lipopolysaccharides and conjugates thereof, and methods of use thereof.

公开(公告)号：US20250114442A1

公开(公告)日：2025-04-10

申请号：US18828443

申请日：2024-09-09

Applicant: Pfizer Inc.

Inventor： Annaliesa Sybil Anderson ,  Laurent Oliver Chorro ,  Robert George Konrad Donald ,  Jacqueline Marie Lypowy ,  Rosalind Pan

IPC: A61K39/108 ,  A61K39/00 ,  A61P31/04 ,  A61P37/04

Abstract: This invention relates to compositions that include a polypeptide derived from E. coli or a fragment thereof; and modified O-polysaccharide molecules derived from E. coli lipopolysaccharides and conjugates thereof, and methods of use thereof.

公开(公告)号：US20220152181A1

公开(公告)日：2022-05-19

申请号：US17509110

申请日：2021-10-25

Applicant: Pfizer Inc.

Inventor： Annaliesa Sybil Anderson ,  Laurent Oliver Chorro ,  Robert George Konrad Donald ,  Jacqueline Marie Lypowy ,  Rosalind Pan

IPC: A61K39/108 ,  A61P31/04 ,  A61P37/04

Abstract: This invention relates to compositions that include a polypeptide derived from E. coli or a fragment thereof; and modified O-polysaccharide molecules derived from E. coli lipopolysaccharides and conjugates thereof, and methods of use thereof.