-
公开(公告)号:US20220033784A1
公开(公告)日:2022-02-03
申请号:US17371206
申请日:2021-07-09
Applicant: Pfizer Inc.
Inventor: Joseph John Binder , Michael Dale Eisenbraun , Clare Lees , Jeremy Shawn Myers , James Travis Patterson
IPC: C12N7/00 , C07K14/55 , A61K35/768 , A61P35/00
Abstract: The present disclosure provides human IL-2 variants, recombinant oncolytic viruses comprising the IL-2 variant, compositions comprising the IL-2 variant or recombinant oncolytic virus, and use of the IL-2 variants, recombinant oncolytic virus, or compositions for treating cancer in an individual.