公开(公告)号：US20250129057A1

公开(公告)日：2025-04-24

申请号：US18685644

申请日：2022-08-25

Applicant: Pfizer Inc.

Inventor： Scott W. Bagley ,  Wesley Dewitt Clark ,  David Andrew Griffith ,  Wenhua Jiao ,  Brian Matthew Samas ,  Lisa Jane Taylor

IPC: C07D405/14 ,  A61K31/4545

Abstract: The invention provides solid forms of 2-[(4-{6-[(4-Cyano-2-fluorobenzyl)oxy]pyridin-2-yl}piperidin-1-yl)methyl]-1-[(2S)-oxetan-2-ylmethyl]-1H-benzimidazole-6-carboxylic acid, 1,3-dihydroxy-2-(hydroxymethyl) propan-2-amine salt for example, Form 1 or Form 2; as well as pharmaceutical compositions, and the uses thereof in treating diseases, conditions or disorders modulated by GLP-1R in a mammal, such as a human.