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![Polymorphs of (1S,2S,3S,5R)-3-((6-(Difluoromethyl)-5-Fluoro-1,2,3,4-Tetrahydroisoquinolin-8-YL)OXY)-5-(4-Methyl-7H-Pyrrolo[2,3-D]Pyrimidin-7-YL)Cyclopentane-1,2-DIOL Mono-Hydrochloride](/abs-image/US/2023/08/03/US20230242539A1/abs.jpg.150x150.jpg)
公开(公告)号：US20230242539A1
公开(公告)日：2023-08-03
申请号：US18004965
申请日：2021-07-08
Applicant: Pfizer Inc.
IPC: C07D487/04
CPC classification number: C07D487/04 , C07B2200/13
Abstract: This invention relates to crystalline mono-HCl salt forms of (1S,2S,3S,5R)-3-((6-(difluoromethyl)-5-fluoro-1,2,3,4-tetrahydroisoquinolin-8-yl)oxy)-5-(4-methyl-7H-pyrrolo[2,3-d]pyrimidin-7-yl)cyclopentane-1,2-diol, and to compositions and therapeutic uses thereof.
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