公开(公告)号：US20230365701A1

公开(公告)日：2023-11-16

申请号：US18315054

申请日：2023-05-10

Applicant: Pfizer Inc.

Inventor： James Reasoner APGAR ,  Bas Joannes Gertrudis BAATEN ,  Aruna BITRA ,  Javier Fernando CHAPARRO RIGGERS ,  Giuseppe DI CARO ,  Pawel Kamil DOMINIK ,  Zachary John MABEN ,  Lidia MOSYAK ,  Andrew Ross NAGER ,  Cecilia Marianne ODERUP ,  Edward Derrick PASCUA ,  Shahram SALEK-ARDAKANI ,  Dirk Michael ZAJONC

IPC: C07K16/28 ,  A61P35/00

CPC classification number: C07K16/2878 ,  A61P35/00 ,  C07K2317/35 ,  C07K2317/71 ,  C07K2317/92 ,  A61K2039/505

Abstract: Antibodies that specifically bind to LTBR are provided. Also provided are uses of these antibodies, and related compositions and methods.

公开(公告)号：US20220370606A1

公开(公告)日：2022-11-24

申请号：US17415348

申请日：2019-12-18

Applicant: Pfizer Inc.

Inventor： Shih-Hsun CHEN ,  Luca MICCI ,  Cecilia Marianne ODERUP ,  Shahram SALEK-ARDAKANI ,  Jie WEI

IPC: A61K39/395 ,  C07K16/28 ,  A61P35/00 ,  A61K31/713 ,  A61K31/7125

Abstract: The present disclosure describes combination therapies and uses thereof for the treatment of cancer. The combinations therapies include at least a first therapeutic agent and a second therapeutic agent.

公开(公告)号：US20240124591A1

公开(公告)日：2024-04-18

申请号：US18319943

申请日：2023-05-18

Applicant: Pfizer Inc.

Inventor： Javier Fernando CHAPARRO RIGGERS ,  Shih-Hsun CHEN ,  Sheng DING ,  Pawel Kamil DOMINIK ,  Shahram SALEK-ARDAKANI ,  Jessica Lynn Stanfield ,  Thomas John VAN BLARCOM

IPC: C07K16/28 ,  A61P35/00

CPC classification number: C07K16/2827 ,  A61P35/00 ,  C07K16/2803 ,  A61K2039/505

Abstract: Antibodies that specifically bind to CD47 and antibodies that specifically bind to PD-L1 are provided, as well as CD47/PD-L1 bispecific antibodies. Also provided are uses of these antibodies, and related compositions and methods.

公开(公告)号：US20210179716A1

公开(公告)日：2021-06-17

申请号：US17120935

申请日：2020-12-14

Applicant: Pfizer Inc.

Inventor： Javier Fernando CHAPARRO RIGGERS ,  Shih-Hsun CHEN ,  Sheng DING ,  Pawel Kamil DOMINIK ,  Shahram SALEK-ARDAKANI ,  Jessica Lynn Stanfield ,  Thomas John VAN BLARCOM

IPC: C07K16/28 ,  A61P35/00

Abstract: Antibodies that specifically bind to CD47 and antibodies that specifically bind to PD-L1 are provided, as well as CD47/PD-L1 bispecific antibodies. Also provided are uses of these antibodies, and related compositions and methods.