公开(公告)号：US20230165788A1

公开(公告)日：2023-06-01

申请号：US17995542

申请日：2021-04-07

Applicant: Research Triangle Institute

Inventor： Leah Marie JOHNSON ,  Linying Alice LI ,  Sai Archana KROVI ,  Ariane VAN DER STRATEN

IPC: A61K9/00 ,  A61K31/7076 ,  A61K31/675 ,  A61K45/06 ,  A61K47/44 ,  A61K47/34 ,  A61P31/18 ,  A61K31/575 ,  A61K31/57 ,  A61P15/18

CPC classification number: A61K9/0024 ,  A61K31/57 ,  A61K31/575 ,  A61K31/675 ,  A61K31/7076 ,  A61K45/06 ,  A61K47/34 ,  A61K47/44 ,  A61P15/18 ,  A61P31/18

Abstract: A reservoir device comprising an active agent formulation contained within a reservoir is described. The active agent formulation comprises more than one active agent. The reservoir is defined by a biodegradable, permeable polymer membrane. The membrane allows for diffusion of the more than one active agent of the formulation there through when positioned subcutaneously in a body of a subject.

公开(公告)号：US20210346661A1

公开(公告)日：2021-11-11

申请号：US17284989

申请日：2019-10-16

Applicant: Research Triangle Institute

Inventor： Leah Marie JOHNSON ,  Ariane VAN DER STRATEN ,  Ginger Denison ROTHROCK ,  Linying Alice LI ,  Ellen LUECKE ,  Natalie GIROUARD ,  Zach Richard DEMKOVICH ,  Sai Archana KROVI

IPC: A61M31/00 ,  A61L27/18 ,  A61L27/54 ,  A61L27/58 ,  A61K9/00

Abstract: A reservoir device comprising an active agent formulation contained within a reservoir is described. The reservoir is defined by a biodegradable, permeable polymer membrane having a thickness of at least 45 μm. The membrane allows for diffusion of an active agent of the formulation there through when positioned subcutaneously in a body of a subject.