公开(公告)号：US4927624A

公开(公告)日：1990-05-22

申请号：US123007

申请日：1987-11-19

申请人： Robert G. Bryant ,  Jay J. Listinsky

发明人： Robert G. Bryant ,  Jay J. Listinsky

IPC分类号： A61K49/06 ,  A61K49/18 ,  G01R33/28

CPC分类号： G01R33/5601 ,  A61K49/06 ,  A61K49/1806 ,  Y10T436/24

摘要： Contrast medium compositions for delineation of bowel during magnetic resonance imaging (MRI) of the abdomen are provided for oral or rectal administration. The compositions consist of aqueous suspensions of clay in finely-divided particles which expose a large surface area to the suspending water and impose a condition of dynamic anisotropy upon the adjacent water, resulting in reduction predominantly in the transverse relaxation time of the water and subsequent loss of signal from the bowel lumen.

摘要翻译： 用于在腹部磁共振成像（MRI）下用于描绘肠的对比培养基组合物用于口服或直肠给药。 组合物由细碎颗粒中的粘土的水性悬浮液组成，其将大的表面积暴露于悬浮水并且在相邻的水上施加动态各向异性的条件，导致主要在水的横向弛豫时间和随后的损失 来自肠腔的信号。