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公开(公告)号：US20200246476A1
公开(公告)日：2020-08-06
申请号：US16852931
申请日：2020-04-20
Applicant: Roche Diagnostics Operations, Inc.
Inventor： Harmut Duefel , Uwe Kobold , Andreas Leinenbach
Abstract: The present disclosure is directed at an antibody conjugate having an antibody and a tag, wherein one or more element(s) present in the antibody exhibit an isotope ratio which differs from the naturally occurring isotope ratio of the one or more element(s), wherein the amount of the isotope which is less-common in nature, is increased to at least 4% of the atoms of the respective element in the antibody, as well as uses thereof.
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公开(公告)号：US11491236B2
公开(公告)日：2022-11-08
申请号：US16852931
申请日：2020-04-20
Applicant: Roche Diagnostics Operations, Inc.
Inventor： Harmut Duefel , Uwe Kobold , Andreas Leinenbach
Abstract: The present disclosure is directed at an antibody conjugate having an antibody and a tag, wherein one or more element(s) present in the antibody exhibit an isotope ratio which differs from the naturally occurring isotope ratio of the one or more element(s), wherein the amount of the isotope which is less-common in nature, is increased to at least 4% of the atoms of the respective element in the antibody, as well as uses thereof.
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