公开(公告)号：US20250116670A1

公开(公告)日：2025-04-10

申请号：US18908787

申请日：2024-10-07

Applicant: Roche Diagnostics Operations, Inc.

Inventor： Christa Cobbaert ,  Konstantin Kroeniger ,  Guinevere Lageveen-Kammeijer ,  Jan Nouta ,  Vinzent Rolny ,  Renee Ruhaak ,  Magdalena Swiatek-de Lange ,  Gloria Tabares ,  Yuri van der Burgt ,  Manfred Wuhrer

IPC: G01N33/574 ,  G01N33/573

Abstract: The present invention relates to methods for assessing whether or not a patient has aggressive prostate cancer by determining the levels of particular glycoforms attached to prostate specific antigen (PSA) protein in a biofluid sample of a subject, and comparing the determined level or concentration to a reference. The methods are particularly useful for assessing subjects that have 2-10 ng/ml total PSA in the subject's serum.