公开(公告)号：US20150183743A1

公开(公告)日：2015-07-02

申请号：US14412329

申请日：2013-07-04

Applicant: STICHTING VU-VUMC

Inventor： Johannes Antonius Maria Christiaans ,  Albert Dirk Windhorst ,  Athanasios Metaxas ,  Pieter Jacob Klein ,  Esther Johanna Maria Kooijman ,  Bart Nicolaas Maria Van Berckel

IPC: C07D213/74

CPC classification number: C07D213/74 ,  C07C213/02 ,  C07C2601/02 ,  C07C2601/08 ,  C07D213/24 ,  C07D213/38 ,  C07C215/74

Abstract: The invention is directed to a compound according to formula (1) wherein R2 is fluorine, X is nitrogen or carbon and R3 is an organic group. The invention is also directed to the use of this compound as a precursor for the preparation of a 11C or 18F-radio labelled compound. The radio labelled compound may be used in an in vivo diagnostic or imaging method.

Abstract translation: 本发明涉及式（1）的化合物，其中R 2是氟，X是氮或碳，R 3是有机基团。 本发明还涉及该化合物作为制备11C或18F-无线电标记化合物的前体的用途。 放射性标记的化合物可以用于体内诊断或成像方法。