公开(公告)号：US20240279171A1

公开(公告)日：2024-08-22

申请号：US18565618

申请日：2022-06-02

Applicant: SUNOVION PHARMACEUTICALS INC.

Inventor： Robert Joseph PRYTKO ,  John R. SNOONIAN ,  Harold Scott WILKINSON ,  Anna BALANOV

IPC: C07D207/09 ,  A61K31/40

CPC classification number: C07D207/09 ,  A61K31/40

Abstract: Provided are methods for making crystalline forms of (S)-(−)-amisulpride and (R)-(+)-amisulpride. Also provided are pharmaceutical compositions comprising the crystalline forms of (S)-(−)-amisulpride and (R)-(+)-amisulpride and methods of using the crystalline forms.

公开(公告)号：US20200290987A1

公开(公告)日：2020-09-17

申请号：US16817749

申请日：2020-03-13

Applicant: Sunovion Pharmaceuticals Inc.

Inventor： Nandkumar Nivritti BHOGLE ,  Takahiko HASHIZUKA ,  Robert Joseph PRYTKO ,  John R. SNOONIAN ,  Harold Scott WILKINSON ,  Haitao ZHANG

IPC: C07D311/76

Abstract: The present disclosure relates to salts of (R)-1-(8-fluoroisochroman-1-yl)-N-methylmethanamine, crystalline forms thereof, and methods of preparation thereof, which are useful in the treatment of CNS disorders.

公开(公告)号：US20220098163A1

公开(公告)日：2022-03-31

申请号：US17347709

申请日：2021-06-15

Applicant: Sunovion Pharmaceuticals Inc.

Inventor： Nandkumar Nivritti BHOGLE ,  Takahiko HASHIZUKA ,  Robert Joseph PRYTKO ,  John R. SNOONIAN ,  Harold Scott WILKINSON ,  Haitao ZHANG

IPC: C07D311/76

Abstract: The present disclosure relates to salts of (R)-1-(8-fluoroisochroman-1-yl)-N-methylmethanamine, crystalline forms thereof, and methods of preparation thereof, which are useful in the treatment of CNS disorders.