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公开(公告)号：US20180222845A1
公开(公告)日：2018-08-09
申请号：US15786917
申请日：2017-10-18
发明人： Paul McGlynn , Roger BAKALE , Craig STURGE
IPC分类号： C07C215/60 , A61M15/00 , C09K3/30 , A61K9/00 , A61K31/205 , A61K9/14 , C07C59/255
CPC分类号： C07C215/60 , A61K9/008 , A61K9/14 , A61K31/205 , A61M15/002 , A61M15/009 , A61M2202/0484 , A61M2202/0488 , A61M2202/064 , C07B2200/07 , C07B2200/13 , C07C59/255 , C09K3/30
摘要： Levalbuterol L-tartrate affords crystals possessing properties desirable for use in a metered dose inhaler.
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公开(公告)号：US08765153B2
公开(公告)日：2014-07-01
申请号：US13873084
申请日：2013-04-29
发明人： Paul McGlynn , Roger Bakale , Craig Sturge
IPC分类号： C07C215/60 , A61K31/205 , A61M15/00 , A61K9/14 , C07C59/255 , A61K9/00 , C09K3/30
CPC分类号： C07C215/60 , A61K9/008 , A61K9/14 , A61K31/205 , A61M15/002 , A61M15/009 , A61M2202/0484 , A61M2202/0488 , A61M2202/064 , C07B2200/07 , C07B2200/13 , C07C59/255 , C09K3/30
摘要： Levalbuterol L-tartrate affords crystals possessing properties desirable for use in a metered dose inhaler.
摘要翻译： 莱伐珠特醇L-酒石酸盐提供具有期望用于计量剂量吸入器的性质的晶体。
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公开(公告)号：US20140135300A1
公开(公告)日：2014-05-15
申请号：US14157793
申请日：2014-01-17
IPC分类号： C07C233/43 , A61K31/4015 , A61K45/06 , A61K31/167
CPC分类号： C07C233/43 , A61K9/0075 , A61K9/008 , A61K31/167 , A61K31/4015 , A61K45/06 , C07B2200/13 , C07C231/18
摘要： The compound of formula (I) is a water-stable, long acting β2-selective adrenoceptor agonist useful as a bronchodilator in the treatment of bronchoconstriction associated with reversible obstructive airways diseases and the like. Processes for making the compound of formula (I), as well as related intermediates, are disclosed.
摘要翻译： 式（I）化合物是用作治疗与可逆性阻塞性气道疾病等相关的支气管收缩剂的支气管扩张剂的水稳定性长效β2-选择性肾上腺素受体激动剂。 公开了制备式（I）化合物以及相关中间体的方法。
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公开(公告)号：US20130296607A1
公开(公告)日：2013-11-07
申请号：US13934996
申请日：2013-07-03
IPC分类号： C07C231/18
CPC分类号： C07C233/43 , A61K9/0075 , A61K9/008 , A61K31/167 , A61K31/4015 , A61K45/06 , C07B2200/13 , C07C231/18
摘要： The compound of formula (I) is a water-stable, long acting β2-selective adrenoceptor agonist useful as a bronchodilator in the treatment of bronchoconstriction associated with reversible obstructive airways diseases and the like. Processes for making the compound of formula (I), as well as related intermediates, are disclosed.
摘要翻译： 式（I）化合物是用作治疗与可逆性阻塞性气道疾病等相关的支气管收缩剂的支气管扩张剂的水稳定的长效β2-选择性肾上腺素受体激动剂。 公开了制备式（I）化合物以及相关中间体的方法。
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公开(公告)号：US09040588B2
公开(公告)日：2015-05-26
申请号：US14157793
申请日：2014-01-17
IPC分类号： C07C233/43 , A61K31/167 , A61K31/4015 , A61K45/06 , C07C231/18
CPC分类号： C07C233/43 , A61K9/0075 , A61K9/008 , A61K31/167 , A61K31/4015 , A61K45/06 , C07B2200/13 , C07C231/18
摘要： The compound of formula (I) is a water-stable, long acting β2-selective adrenoceptor agonist useful as a bronchodilator in the treatment of bronchoconstriction associated with reversible obstructive airways diseases and the like. Processes for making the compound of formula (I), as well as related intermediates, are disclosed.
摘要翻译： 式（I）化合物是用作治疗与可逆性阻塞性气道疾病等相关的支气管收缩剂的支气管扩张剂的水稳定性长效β2-选择性肾上腺素受体激动剂。 公开了制备式（I）化合物以及相关中间体的方法。
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公开(公告)号：US09499476B2
公开(公告)日：2016-11-22
申请号：US14692843
申请日：2015-04-22
IPC分类号： C07C233/43 , A61K9/00 , A61K45/06 , A61K31/167 , C07C231/18 , A61K31/4015
CPC分类号： C07C233/43 , A61K9/0075 , A61K9/008 , A61K31/167 , A61K31/4015 , A61K45/06 , C07B2200/13 , C07C231/18
摘要： The compound of formula (I) is a water-stable, long acting β2-selective adrenoceptor agonist useful as a bronchodilator in the treatment of bronchoconstriction associated with reversible obstructive airways diseases and the like. Processes for making the compound of formula (I), as well as related intermediates, are disclosed.
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公开(公告)号：US20160368858A1
公开(公告)日：2016-12-22
申请号：US15003883
申请日：2016-01-22
发明人： Paul McGlynn , Roger Bakale , Craig Sturge
IPC分类号： C07C215/60 , A61M15/00 , C07C59/255
CPC分类号： C07C215/60 , A61K9/008 , A61K9/14 , A61K31/205 , A61M15/002 , A61M15/009 , A61M2202/0484 , A61M2202/0488 , A61M2202/064 , C07B2200/07 , C07B2200/13 , C07C59/255 , C09K3/30
摘要： Levalbuterol L-tartrate affords crystals possessing properties desirable for use in a metered dose inhaler.
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公开(公告)号：US08664441B2
公开(公告)日：2014-03-04
申请号：US13934996
申请日：2013-07-03
IPC分类号： C07C233/05
CPC分类号： C07C233/43 , A61K9/0075 , A61K9/008 , A61K31/167 , A61K31/4015 , A61K45/06 , C07B2200/13 , C07C231/18
摘要： The compound of formula (I) is a water-stable, long acting β2-selective adrenoceptor agonist useful as a bronchodilator in the treatment of bronchoconstriction associated with reversible obstructive airways diseases and the like. Processes for making the compound of formula (I), as well as related intermediates, are disclosed.
摘要翻译： 式（I）化合物是用作治疗与可逆性阻塞性气道疾病等相关的支气管收缩剂的支气管扩张剂的水稳定的长效β2-选择性肾上腺素受体激动剂。 公开了制备式（I）化合物以及相关中间体的方法。
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