公开(公告)号：US09834520B2

公开(公告)日：2017-12-05

申请号：US14775514

申请日：2014-03-13

Applicant: TAKEDA PHARMACEUTICAL COMPANY LIMITED

Inventor： Satoshi Yamamoto ,  Junya Shirai ,  Yoshiyuki Fukase ,  Ayumu Sato ,  Mitsunori Kouno ,  Yoshihide Tomata ,  Atsuko Ochida ,  Kazuko Yonemori ,  Tsuneo Oda ,  Tomoya Yukawa

IPC: A61K31/517 ,  C07D239/72 ,  C07D239/96 ,  C07D403/12 ,  C07D401/12 ,  C07D409/12 ,  C07D239/80 ,  C07D413/12 ,  C07D417/12 ,  C07D471/04 ,  C07D265/36 ,  C07D217/24 ,  C07D405/06 ,  C07D475/04 ,  C07F7/08

CPC classification number: C07D239/96 ,  C07D217/24 ,  C07D239/80 ,  C07D265/36 ,  C07D401/12 ,  C07D403/12 ,  C07D405/06 ,  C07D409/12 ,  C07D413/12 ,  C07D417/12 ,  C07D471/04 ,  C07D475/04 ,  C07F7/0812

Abstract: The present invention provides a heterocyclic compound having an RORγt inhibitory action.The present invention relates to a compound represented by the formula (I): wherein Ar is a the partial structure (1) to the partial structure (5), Q is a bivalent group selected from the group consisting of (Ia)-(If), and B is a ring optionally having substituent(s), or a salt thereof.

公开(公告)号：US20160229814A1

公开(公告)日：2016-08-11

申请号：US14775514

申请日：2014-03-13

Applicant: TAKEDA PHARMACEUTICAL COMPANY LIMITED

Inventor： Satoshi Yamamoto ,  Junya Shirai ,  Yoshiyuki Fukase ,  Ayumu Sato ,  Mitsunori Kouno ,  Yoshihide Tomata ,  Atsuko Ochida ,  Kazuko Yonemori ,  Tsuneo Oda ,  Takashi Imada ,  Tomoya Yukawa

IPC: C07D239/96 ,  C07D265/36 ,  C07F7/08 ,  C07D401/12 ,  C07D217/24 ,  C07D417/12 ,  C07D409/12 ,  C07D413/12 ,  C07D475/04 ,  C07D405/06 ,  C07D471/04 ,  C07D403/12

CPC classification number: C07D239/96 ,  C07D217/24 ,  C07D239/80 ,  C07D265/36 ,  C07D401/12 ,  C07D403/12 ,  C07D405/06 ,  C07D409/12 ,  C07D413/12 ,  C07D417/12 ,  C07D471/04 ,  C07D475/04 ,  C07F7/0812

Abstract: The present invention provides a heterocyclic compound having an RORγt inhibitory action.The present invention relates to a compound represented by the formula (I): wherein Ar is a the partial structure (1) to the partial structure (5), Q is a bivalent group selected from the group consisting of (Ia)-(If), and B is a ring optionally having substituent(s), or a salt thereof.

Abstract translation: 本发明提供具有RORγt抑制作用的杂环化合物。 本发明涉及由式（I）表示的化合物：其中Ar是部分结构（5）的部分结构（1），Q是选自（Ia） - （If ），B是任选具有取代基的环或其盐。