公开(公告)号：US20240294670A1

公开(公告)日：2024-09-05

申请号：US17996854

申请日：2021-04-21

Applicant: THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM

Inventor： Cynthia JU ,  Jongmin JEONG ,  Zhao SHAN ,  Leike LI ,  Ningyan AN ,  Zhiqiang AN

IPC: C07K16/40 ,  A61K39/00 ,  A61K45/06 ,  A61P35/00

CPC classification number: C07K16/40 ,  A61K39/4631 ,  A61K45/06 ,  A61P35/00 ,  A61K2039/505 ,  A61K2239/13 ,  C07K2317/11 ,  C07K2317/24 ,  C07K2317/31 ,  C07K2317/52 ,  C07K2317/565

Abstract: Provided herein are antibodies binding to CHI3L1 and the uses of the antibodies in detecting and treating cancer and for treating hepatotoxicity.