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公开(公告)号：US20180271848A1
公开(公告)日：2018-09-27
申请号：US15571240
申请日：2016-05-02
Inventor： Lawrence LUM , Chuo CHEN , Xuewu ZHANG , Ozlem KULAK , Xiaofeng WU
IPC: A61K31/454 , A61K45/06
Abstract: The present disclosure provides compounds that may be useful for inhibiting the Tankyrase enzyme. In some aspects, these compounds are useful in the treatment of a disease or disorder related to the misregulation of Tankyrase enzyme such as cancer, degenerative diseases, or fibrotic diseases. Also provided herein are compounds may also be used to prevent the elongation of the telomere in a cell.
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