公开(公告)号：US09689954B2

公开(公告)日：2017-06-27

申请号：US14041092

申请日：2013-09-30

申请人： Xuebei Yang ,  Charles Chen ,  Payam Seifi ,  Aydin Babakhani

发明人： Xuebei Yang ,  Charles Chen ,  Payam Seifi ,  Aydin Babakhani

IPC分类号： G01R33/60 ,  G01R33/30

CPC分类号： G01R33/60 ,  G01R33/302

摘要： An integrated electron spin resonance (ESR) circuit chip includes a chip substrate, a transmitter circuit, and a receiver circuit. The transmitter circuit and receiver circuit are disposed on the chip substrate. The transmitter circuit includes an oscillator circuit configured to generate an oscillating output signal and a power amplifier (PA) circuit configured to generate an amplified oscillating output signal based on the oscillating output signal. The receiver circuit receives an ESR signal from an ESR probe. The receiver circuit includes a receiver amplifier circuit configured to generate an amplified ESR signal based on the received ESR signal, a mixer circuit configured to receive the amplified ESR signal and to down-convert the amplified ESR signal to a baseband signal, and a baseband amplifier circuit configured to generate an amplified baseband signal based on the baseband signal.

公开(公告)号：US09857447B2

公开(公告)日：2018-01-02

申请号：US14041212

申请日：2013-09-30

申请人： Xuebei Yang ,  Charles Chen ,  Payam Seifi ,  Aydin Babakhani

发明人： Xuebei Yang ,  Charles Chen ,  Payam Seifi ,  Aydin Babakhani

IPC分类号： G01R33/60 ,  G01R33/30

CPC分类号： G01R33/60 ,  G01R33/302

摘要： A method includes generating, from an integrated oscillator circuit, an oscillating output signal and generating, by an integrated power amplifier (PA) circuit, an amplified oscillating output signal based on the oscillating output signal. The method further includes receiving, by integrated receiver amplifier circuit, an electron spin resonance (ESR) signal from biological samples that include a magnetic species and generating, by the integrated receiver amplifier circuit, an amplified ESR signal based on the received ESR signal. The method further includes receiving, by the integrated receiver amplifier circuit, an electron spin resonance (ESR) signal from magnetic nanoparticles that are loaded with drugs or attached to human cells.

公开(公告)号：US20170242091A1

公开(公告)日：2017-08-24

申请号：US15591623

申请日：2017-05-10

申请人： Xuebei Yang ,  Charles Chen ,  Payam Seifi ,  Aydin Babakhani

发明人： Xuebei Yang ,  Charles Chen ,  Payam Seifi ,  Aydin Babakhani

IPC分类号： G01R33/60

CPC分类号： G01R33/60 ,  G01R33/302

摘要： An integrated electron spin resonance (ESR) circuit chip includes a chip substrate, a transmitter circuit, and a receiver circuit. The transmitter circuit and receiver circuit are disposed on the chip substrate. The transmitter circuit includes an oscillator circuit configured to generate an oscillating output signal and a power amplifier (PA) circuit configured to generate an amplified oscillating output signal based on the oscillating output signal. The receiver circuit receives an ESR signal from an ESR probe. The receiver circuit includes a receiver amplifier circuit configured to generate an amplified ESR signal based on the received ESR signal, a mixer circuit configured to receive the amplified ESR signal and to down-convert the amplified ESR signal to a baseband signal, and a baseband amplifier circuit configured to generate an amplified baseband signal based on the baseband signal.

公开(公告)号：US20140097842A1

公开(公告)日：2014-04-10

申请号：US14041212

申请日：2013-09-30

申请人： Xuebei Yang ,  Charles Chen ,  Payam Seifi ,  Aydin Babakhani

发明人： Xuebei Yang ,  Charles Chen ,  Payam Seifi ,  Aydin Babakhani

IPC分类号： G01R33/60

CPC分类号： G01R33/60 ,  G01R33/302

摘要： A method includes generating, from an integrated oscillator circuit, an oscillating output signal and generating, by an integrated power amplifier (PA) circuit, an amplified oscillating output signal based on the oscillating output signal. The method further includes receiving, by integrated receiver amplifier circuit, an electron spin resonance (ESR) signal from biological samples that include a magnetic species and generating, by the integrated receiver amplifier circuit, an amplified ESR signal based on the received ESR signal. The method further includes receiving, by the integrated receiver amplifier circuit, an electron spin resonance (ESR) signal from magnetic nanoparticles that are loaded with drugs or attached to human cells.

摘要翻译： 一种方法包括从集成振荡器电路产生振荡输出信号，并且通过集成功率放大器（PA）电路产生基于振荡输出信号的放大的振荡输出信号。 该方法还包括通过集成接收放大器电路从包括磁性物质的生物样品接收电子自旋共振（ESR）信号，并通过集成接收机放大器电路产生基于所接收的ESR信号的放大的ESR信号。 该方法还包括由集成接收放大器电路接收来自装载药物或附着于人细胞的磁性纳米粒子的电子自旋共振（ESR）信号。

公开(公告)号：US20140091802A1

公开(公告)日：2014-04-03

申请号：US14041092

申请日：2013-09-30

申请人： Xuebei Yang ,  Charles Chen ,  Payam Seifi ,  Aydin Babakhani

发明人： Xuebei Yang ,  Charles Chen ,  Payam Seifi ,  Aydin Babakhani

IPC分类号： G01R33/60

CPC分类号： G01R33/60 ,  G01R33/302

摘要： An integrated electron spin resonance (ESR) circuit chip includes a chip substrate, a transmitter circuit, and a receiver circuit. The transmitter circuit and receiver circuit are disposed on the chip substrate. The transmitter circuit includes an oscillator circuit configured to generate an oscillating output signal and a power amplifier (PA) circuit configured to generate an amplified oscillating output signal based on the oscillating output signal. The receiver circuit receives an ESR signal from an ESR probe. The receiver circuit includes a receiver amplifier circuit configured to generate an amplified ESR signal based on the received ESR signal, a mixer circuit configured to receive the amplified ESR signal and to down-convert the amplified ESR signal to a baseband signal, and a baseband amplifier circuit configured to generate an amplified baseband signal based on the baseband signal.

摘要翻译： 集成电子自旋谐振（ESR）电路芯片包括芯片基板，发射机电路和接收机电路。 发射机电路和接收器电路设置在芯片基板上。 发射机电路包括被配置为产生振荡输出信号的振荡器电路和被配置为基于振荡输出信号产生放大的振荡输出信号的功率放大器（PA）电路。 接收器电路从ESR探头接收ESR信号。 接收机电路包括：接收放大器电路，被配置为基于所接收的ESR信号产生放大的ESR信号;混频电路，被配置为接收放大的ESR信号并将放大的ESR信号下变频为基带信号;以及基带放大器 电路，被配置为基于所述基带信号生成放大的基带信号。