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公开(公告)号:US20250090510A1
公开(公告)日:2025-03-20
申请号:US18964396
申请日:2024-11-30
Applicant: YEDA RESEARCH AND DEVELOPMENT CO. LTD.
Inventor: Rivka DIKSTEIN , Urmila SERAWAT , Ana TAMARKIN BEN-HARUSH , Ora HAIMOV , Neta REGEV-RUDZKI , Shaked ASHKENAZI , Benjamin WEISS , Anastasia LEV
IPC: A61K31/44 , A61K31/415 , A61K31/428
Abstract: Methods of inhibiting eIF4G1 binding to eIF1, and inhibiting translation initiation are provided. Pharmaceutical compositions comprising inhibitors of eIF4G1-eIF1 binding and there use in treating disease are also provided.