公开(公告)号：US5210299A

公开(公告)日：1993-05-11

申请号：US833087

申请日：1992-02-10

申请人： Yujiro Goto ,  Mitsuaki Yagisawa ,  Masao Kitano

发明人： Yujiro Goto ,  Mitsuaki Yagisawa ,  Masao Kitano

IPC分类号： C07C303/44 ,  C07C303/36 ,  C07C311/03

CPC分类号： C07C303/36

摘要： A method for the production of N-(2-chloroethyl) methanesulfonamide of high purity, which method comprises causing methanesulfonyl chloride to react with ethylene imine in the presence of ethylene dichloride and then distilling there resultant reaction mixture thereby separating therefrom N-(2-chloroethyl) methanesulfonamide, if necessary subjecting the resultant reaction mixture to extraction from water, separating the aqueous layer consequently formed, and subjecting the organic layer resulting from said extraction to distillation thereby separating N-(2-chloroetyl) methanesulfonamide.

摘要翻译： 一种制备高纯度N-（2-氯乙基）甲磺酰胺的方法，该方法包括使甲磺酰氯与乙烯亚胺在二氯乙烷存在下反应，然后蒸馏得到反应混合物，由此分离出N-（2- 氯乙基）甲磺酰胺，如果需要，将所得反应混合物从水中萃取，分离由此形成的水层，并将由所述萃取产生的有机层进行蒸馏，由此分离N-（2-氯乙酰基）甲磺酰胺。

公开(公告)号：US5066813A

公开(公告)日：1991-11-19

申请号：US489672

申请日：1990-03-07

申请人： Masao Kitano ,  Mitsuaki Yagisawa ,  Yutaka Morimoto

发明人： Masao Kitano ,  Mitsuaki Yagisawa ,  Yutaka Morimoto

IPC分类号： C07D277/14

CPC分类号： C07D277/14

摘要： A method for the production of a 1,3-thiazolidin-2-one represented by the general formula II: ##STR1## wherein R.sup.1, R.sup.2, R.sup.3, and R.sup.4 are independently hydrogen atom or a lower alkyl group, which method comprises causing a 1,3-thiazolidine represented by the general formula I: ##STR2## wherein R.sup.1, R.sup.2, R.sup.3, R.sup.4 R.sup.5, and R.sup.6 are independently hydrogen atom or a lower alkyl group to react with urea.