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1314 条记录 (耗时 0.043 秒)

    Three-dimensional printed dental appliances using lattices
    91.
    发明授权
    Three-dimensional printed dental appliances using lattices 有权

    公开(公告)号：US10335250B2

    公开(公告)日：2019-07-02

    申请号：US15230193

    申请日：2016-08-05

    申请人： uLab Systems, Inc.

    发明人： Huafeng Wen

    IPC分类号： A61C7/08 ,  A61C7/00 ,  A61C9/00

    摘要： Method and apparatus for fabricating an oral appliance are described for correcting malocclusions on a dentition of a subject. A three-dimensional representation of the dentition may be captured and a free-form structure having a lattice structure which matches at least part of a surface of the dentition is generated. The lattice structure defines a plurality of open spaces such that the free-form structure is at least partially transparent. The lattice structure may then be manufactured by impregnating or covering a coating into or upon the lattice structure such that the oral appliance is formed.

    Quick folding agility ladder
    94.
    发明授权
    Quick folding agility ladder 有权

    公开(公告)号：US10300338B2

    公开(公告)日：2019-05-28

    申请号：US15454873

    申请日：2017-03-09

    申请人： Jenkins Asia Tech (Shanghai) Limited

    发明人： Weng Kin Chen

    IPC分类号： A63B26/00 ,  A63B23/04 ,  A63B69/00

    摘要： A quick folding agility ladder and methods of folding and opening the agility ladder are disclosed. In one embodiment, the quick folding agility ladder can comprise a plurality of rectangular ladder frames and a plurality of ladder rung sleeves connecting the rectangular ladder frames. The plurality of ladder rung sleeves can comprise a first rung sleeve and a second rung sleeve. The agility ladder can be folded into a quadrifolium configuration comprising four petal-shaped portions including a first petal-shaped portion, a second petal-shaped portion, a third petal-shaped portion, and a fourth petal-shaped portion. The first rung sleeve can form at least part of the first petal-shaped portion and the fourth petal-shaped portion and the second rung sleeve can form at least part of the second petal-shaped portion and the third petal-shaped portion.

    Magnetic resonance imaging
    95.
    发明授权
    Magnetic resonance imaging 有权

    公开(公告)号：US10274565B2

    公开(公告)日：2019-04-30

    申请号：US14726375

    申请日：2015-05-29

    申请人： MAGNEPATH PTY LTD

    发明人： Paul Clark

    IPC分类号： G01R33/48 ,  A61B5/055 ,  G01R33/561 ,  G01R33/58 ,  A61B5/00

    摘要： A method of characterising relative proportions of magnetic resonance (MR) chemical species where one or more of the chemical species has a multi-peak MR spectra includes defining an in-phase measurement time window and an out-phase measurement time window relative to a frequency difference between the two dominant spectral peaks of at least one said multi-peak chemical species. The in-phase window captures the signal that is progressing to being maximally in-phase for the two dominant peaks, and the out-phase window captures the signal that is progressing to being maximally out of phase for the two dominant peaks. The method includes identifying an increased upward deviation in the signal over the in-phase window relative to a reference signal decay over the out-phase window, where such upward deviation in the signal over the in-phase window provides an indicator of the increased presence of the one or more multi peak spectral species over the other species.

    Methods and systems for production of DNA libraries directly from FFPE tissue
    98.
    发明授权
    Methods and systems for production of DNA libraries directly from FFPE tissue 有权

    公开(公告)号：US10221444B1

    公开(公告)日：2019-03-05

    申请号：US16053655

    申请日：2018-08-02

    申请人： URIT Medical Electronic Co., Ltd.

    发明人： Tom Cheng Xu

    IPC分类号： C12Q1/6806 ,  C12N15/10

    摘要： Disclosed are methods and compositions for preparing a DNA library from slide-mounted FFPE tissue samples for downstream next-generation sequencing. In one embodiment, a method of preparing the DNA library is disclosed. The method can comprise applying a droplet of a reagent mixture onto a slide-mounted FFPE tissue sample. The reagent mixture can comprise one or more buffer solutions, a cofactor, a nonionic surfactant, a glycerol solution, a gelatin solution, dNTPs, a DNA polymerase, and a primer pool comprising a plurality of forward primers and reverse primers. The method can also comprise stirring the droplet in a circular motion on the slide while scraping portions of the FFPE tissue sample mounted on the slide to yield a reaction mixture. The method can further comprise aspirating the reaction mixture from the slide directly into a pipette tip and dispensing the reaction mixture into a reaction vessel for further amplification.

    Vacuum coagulation probes
    99.
    发明授权
    Vacuum coagulation probes 有权

    公开(公告)号：US10219859B2

    公开(公告)日：2019-03-05

    申请号：US15094830

    申请日：2016-04-08

    申请人： Atricure, Inc.

    发明人： James G. Whayne ,  Sidney D. Fleischman ,  Earl W. Rogers

    IPC分类号： A61B18/14 ,  A61B18/18 ,  A61B18/08 ,  A61B18/00

    摘要： Methods for using a surgical device integrating a suction mechanism with a coagulation mechanism for improving lesion creation capabilities. The device comprises an elongate member having an insulative covering attached about means for coagulating soft tissue. Openings through the covering expose regions of the coagulation-causing elements and are coupled to lumens in the elongate member which are routed to a vacuum source and a fluid source to passively transport fluid along the contacted soft tissue surface in order to push the maximum temperature deeper into tissue.