公开(公告)号：US20150274708A1

公开(公告)日：2015-10-01

申请号：US14434348

申请日：2013-10-03

申请人： Michael W. SEGANISH ,  Jennifer HANISAK ,  Guoqing LI ,  Rui ZHANG ,  Haiqun TANG ,  MERCK SHARP & DOHME CORP.

发明人： W. Michael Seganish ,  Jennifer Hanisak ,  Guoqing Li ,  Rui Zhang ,  Haiqun Tang

IPC分类号： C07D409/14 ,  A61K31/444 ,  A61K31/4439 ,  A61K45/06 ,  A61K31/5377 ,  A61K31/496 ,  C07D405/14 ,  A61K31/497 ,  C07D401/14 ,  C07D401/12

CPC分类号： C07D409/14 ,  A61K31/4439 ,  A61K31/444 ,  A61K31/496 ,  A61K31/497 ,  A61K31/506 ,  A61K31/5377 ,  A61K45/06 ,  C07D401/12 ,  C07D401/14 ,  C07D405/14 ,  C07D417/14 ,  A61K2300/00

摘要： The present invention relates to inhibitors of IRAK4 of Formula (I) and provides compositions comprising such inhibitors, as well as methods therewith for treating IRAK4-mediated or -associated conditions or diseases.

摘要翻译： 本发明涉及式（I）的IRAK4的抑制剂，并提供包含这些抑制剂的组合物，以及其用于治疗IRAK4介导的或相关的病症或疾病的方法。

公开(公告)号：US09118944B2

公开(公告)日：2015-08-25

申请号：US12366599

申请日：2009-02-05

申请人： Jim Chen Chou ,  Rui Zhang

发明人： Jim Chen Chou ,  Rui Zhang

IPC分类号： H04N7/12 ,  H04N21/24 ,  H04N21/2343 ,  H04N19/147 ,  H04N19/115 ,  H04N19/132 ,  H04N19/156 ,  H04N19/174 ,  H04N19/187 ,  H04N19/36

CPC分类号： H04N21/2402 ,  H04N19/115 ,  H04N19/132 ,  H04N19/147 ,  H04N19/156 ,  H04N19/174 ,  H04N19/187 ,  H04N19/36 ,  H04N21/234327

摘要： A method is provided in one example embodiment and includes receiving video data and gathering statistics associated with the video data. At least some of the video data is broken into slices, each of the slices representing a partition in a video frame within the video data. Each frame is encoded with one or more quality layers based on an outgoing rate and based on a number of central processing unit (CPU) cycles, wherein one or more quality layers of the frames are dropped in the encoding process. In more specific embodiments, the statistics relate to how many bits are used for encoding the quality layers of the video data and how much complexity is required for encoding the quality layers of the video data. After the statistics gathering, adjustments to a network rate are executed.

摘要翻译： 在一个示例实施例中提供了一种方法，并且包括接收视频数据并收集与视频数据相关联的统计信息。 视频数据中的至少一些被分解为片，每个片表示视频数据内的视频帧中的分区。 基于输出速率并且基于多个中央处理单元（CPU）周期，每帧对一个或多个质量层进行编码，其中帧的一个或多个质量层在编码处理中被丢弃。 在更具体的实施例中，统计信息涉及用于对视频数据的质量层进行编码的多少位以及对视频数据的质量层进行编码所需的复杂度。 统计采集后，执行网络速率调整。

公开(公告)号：US09023966B2

公开(公告)日：2015-05-05

申请号：US12429137

申请日：2009-04-23

申请人： Rui Zhang ,  Yongchun Tang

发明人： Rui Zhang ,  Yongchun Tang

IPC分类号： C08F228/02 ,  C08F214/16 ,  C08F226/02 ,  C09K8/584

CPC分类号： C09K8/584

摘要： The present invention relates compositions and methods for enhanced oil recovery. The method is directed to employing a water-soluble The present invention relates compositions and methods for enhanced oil recovery (EOR). The method is directed to employing a water-soluble functional polymeric surfactant (FPS), with a medium IFT value, preferably ranged from about 0.1 to about 15 dyne/cm between water phase containing polymeric surfactant and hydrocarbon phase, for recovery of hydrocarbons from subterranean formations. The FPS solution demonstrates a strong interaction with oil and the great potential to increase both volumetric sweep efficiency and microscopic displacement efficiency in EOR.

摘要翻译： 本发明涉及用于提高采油量的组合物和方法。 本方法涉及使用水溶性本发明涉及用于提高采油量（EOR）的组合物和方法。 该方法涉及使用具有中等IFT值的水溶性功能性聚合物表面活性剂（FPS），优选在含水聚合物表面活性剂和烃相之间约0.1至约15达因/厘米，用于从地下回收烃 地层。 FPS解决方案表现出与油的强烈相互作用，并且具有提高EOR中的体积扫描效率和微观位移效率的巨大潜力。

公开(公告)号：US20140353827A1

公开(公告)日：2014-12-04

申请号：US13903828

申请日：2013-05-28

申请人： Yueli Liu ,  Qinglei Zhang ,  Amanda E. Schuckman ,  Rui Zhang

发明人： Yueli Liu ,  Qinglei Zhang ,  Amanda E. Schuckman ,  Rui Zhang

IPC分类号： H01L23/00

CPC分类号： H01L23/5381 ,  H01L23/4821 ,  H01L23/53238 ,  H01L23/538 ,  H01L23/5383 ,  H01L23/5384 ,  H01L23/5385 ,  H01L23/5386 ,  H01L24/09 ,  H01L24/13 ,  H01L24/16 ,  H01L24/17 ,  H01L24/26 ,  H01L24/27 ,  H01L24/33 ,  H01L24/81 ,  H01L24/82 ,  H01L25/0655 ,  H01L25/18 ,  H01L2224/0401 ,  H01L2224/131 ,  H01L2224/16235 ,  H01L2224/16265 ,  H01L2224/1703 ,  H01L2224/171 ,  H01L2224/2746 ,  H01L2224/32225 ,  H01L2224/3303 ,  H01L2224/33505 ,  H01L2224/73204 ,  H01L2224/81192 ,  H01L2224/81193 ,  H01L2224/81411 ,  H01L2224/81455 ,  H01L2224/81463 ,  H01L2224/81466 ,  H01L2224/8147 ,  H01L2224/81472 ,  H01L2224/81479 ,  H01L2224/81481 ,  H01L2224/81484 ,  H01L2224/81487 ,  H01L2224/81815 ,  H01L2924/01028 ,  H01L2924/01029 ,  H01L2924/0103 ,  H01L2924/01047 ,  H01L2924/0105 ,  H01L2924/12042 ,  H01L2924/15192 ,  H01L2924/15311 ,  H01L2924/181 ,  H05K1/185 ,  H05K3/3436 ,  H05K2201/10363 ,  H01L2924/00014 ,  H01L2924/014 ,  H01L2924/04953 ,  H01L2924/04941 ,  H01L2924/01074 ,  H01L2924/01072 ,  H01L2924/0543 ,  H01L2924/01049 ,  H01L2924/0481 ,  H01L2924/0496 ,  H01L2924/00012 ,  H01L2924/00

摘要： Embodiments of the present disclosure are directed towards techniques and configurations for layered interconnect structures for bridge interconnection in integrated circuit assemblies. In one embodiment, an apparatus may include a substrate and a bridge embedded in the substrate. The bridge may be configured to route electrical signals between two dies. An interconnect structure, electrically coupled with the bridge, may include a via structure including a first conductive material, a barrier layer including a second conductive material disposed on the via structure, and a solderable material including a third conductive material disposed on the barrier layer. The first conductive material, the second conductive material, and the third conductive material may have different chemical composition. Other embodiments may be described and/or claimed.

摘要翻译： 本公开的实施例涉及用于集成电路组件中的桥互连的分层互连结构的技术和配置。 在一个实施例中，装置可以包括衬底和嵌入衬底中的桥。 桥可以被配置为在两个管芯之间布置电信号。 与电桥电耦合的互连结构可以包括通孔结构，其包括第一导电材料，包含布置在通孔结构上的第二导电材料的阻挡层，以及包含布置在阻挡层上的第三导电材料的可焊材料。 第一导电材料，第二导电材料和第三导电材料可以具有不同的化学组成。 可以描述和/或要求保护其他实施例。

公开(公告)号：US08785477B2

公开(公告)日：2014-07-22

申请号：US13685454

申请日：2012-11-26

申请人： Peng Lu ,  Rui Zhang ,  Wansong Yu ,  Mingjie Zhu ,  Yilang Chen

发明人： Peng Lu ,  Rui Zhang ,  Wansong Yu ,  Mingjie Zhu ,  Yilang Chen

IPC分类号： C07D487/04

CPC分类号： C07D487/04

摘要： Hexahydropyrrolo[3,4-b]pyrrole derivatives, preparation methods and pharmaceutical uses thereof are provided. Specifically, dipeptidyl peptidase IV inhibitors presented by following formula (I) are provided. Such compounds can be used for treating or preventing the diseases associated with dipeptidyl peptidase IV, such as diabetes, obesity and hyperlipemia. The compounds presented by formula (I) and pharmaceutically acceptable salts thereof, a method for preparing a pharmaceutical composition thereof and their uses in the manufacture of medicaments for treating or preventing the disease associated with dipeptidyl peptidase IV are provided.

摘要翻译： 提供了六氢吡咯并[3,4-b]吡咯衍生物，其制备方法和药物用途。 具体地，提供了由下式（I）表示的二肽基肽酶IV抑制剂。 这些化合物可用于治疗或预防与二肽基肽酶IV相关的疾病，如糖尿病，肥胖症和高脂血症。 提供式（I）化合物及其药学上可接受的盐，其药物组合物的制备方法及其在制备用于治疗或预防与二肽基肽酶IV相关的疾病的药物中的用途。

公开(公告)号：US08732097B2

公开(公告)日：2014-05-20

申请号：US13402751

申请日：2012-02-22

申请人： Rui Zhang ,  Kurt E. Partridge ,  Robert R. Price ,  James M. A. Begole ,  Maurice K. Chu

发明人： Rui Zhang ,  Kurt E. Partridge ,  Robert R. Price ,  James M. A. Begole ,  Maurice K. Chu

IPC分类号： G06F15/18

CPC分类号： G06Q10/04 ,  G06Q30/02

摘要： A recommender system determines a probability threshold for an activity-prediction model, and uses the probability threshold to predict whether a user is performing a target activity. To determine the probability threshold, the system computes a set of activity probabilities based on contextual information for a set of historical activities, and based on an activity-prediction model for a target activity. The system then compares a set of probability thresholds with the set of activity probabilities to determine a prediction success rate for each probability threshold. The system computes a utility score for each probability threshold based on the prediction success rates and a utility function, and selects a probability threshold whose utility score is optimal amongst the utility scores of the set of thresholds and greater than or equal to a baseline utility score. The system then assigns the probability threshold to the activity-prediction model.

摘要翻译： 推荐系统确定活动预测模型的概率阈值，并使用概率阈值来预测用户是否正在执行目标活动。 为了确定概率阈值，系统基于一组历史活动的上下文信息，并且基于目标活动的活动预测模型来计算一组活动概率。 然后，系统将一组概率阈值与活动概率集合进行比较，以确定每个概率阈值的预测成功率。 该系统基于预测成功率和效用函数来计算每个概率阈值的效用得分，并且选择一个概率阈值，其效用评分在阈值集合的效用评分之间是最佳的，并且大于或等于基准效用得分 。 系统然后将概率阈值分配给活动预测模型。

公开(公告)号：US08692048B2

公开(公告)日：2014-04-08

申请号：US13388507

申请日：2010-08-05

申请人： Zhichang Liu ,  Chunming Xu ,  Rui Zhang ,  Xianghai Meng ,  Ana Cecilia Patroni ,  Peter Anton August Klusener ,  Albertus Vincentius Petrus Van Den Bosch

发明人： Zhichang Liu ,  Chunming Xu ,  Rui Zhang ,  Xianghai Meng ,  Ana Cecilia Patroni ,  Peter Anton August Klusener ,  Albertus Vincentius Petrus Van Den Bosch

IPC分类号： C07C7/144

CPC分类号： C07C2/58 ,  C07C2531/14 ,  C07C9/16

摘要： The present invention provides a method for revamping an HF or sulphuric acid alkylation unit to an ionic liquid alkylation unit, wherein the HF or sulphuric acid alkylation unit comprise at least: —a reactor unit for contacting catalyst and hydrocarbon reactants; —a separator unit for separating a reactor effluent into a catalyst phase and an alkylate-comprising hydrocarbon phase; —a fractionator unit for fractionating the alkylate-comprising hydrocarbon phase into at least one stream comprising alkylate; and which method includes: —providing a second separator unit suitable for the separation of solids from liquids downstream of the reactor unit suitable to reduce the solids content in at least part of the reactor effluent.

摘要翻译： 本发明提供了将HF或硫酸烷基化单元改性为离子液体烷基化单元的方法，其中HF或硫酸烷基化单元至少包括： - 用于使催化剂和烃反应物接触的反应器单元; - 用于将反应器流出物分离成催化剂相和含烷基化物烃相的分离器单元; - 用于将含烷基化物烃相分级成至少一种包含烷基化物的流的分馏器单元; 并且哪种方法包括： - 提供适合于从反应器单元下游的液体中分离固体的第二分离器单元，其适于减少至少部分反应器流出物中的固体含量。

公开(公告)号：US20130262216A1

公开(公告)日：2013-10-03

申请号：US13436348

申请日：2012-03-30

申请人： Rui Zhang ,  Richard Chow ,  Maurice Kyojin Chu ,  Kurt E. Partridge

发明人： Rui Zhang ,  Richard Chow ,  Maurice Kyojin Chu ,  Kurt E. Partridge

IPC分类号： G06Q30/02 ,  G06F17/10 ,  G06F7/60

CPC分类号： G06Q30/0631 ,  G06Q30/02

摘要： A performance-efficient activity-modeling system generates a group-activity model for a population group using information from an optimal subset of users of the population group. During operation, the system computes utility scores for a set of users based on a utility-scoring function, such that a respective utility score indicates a usefulness or penalty of collecting a corresponding user's contextual information. The system then selects, from the set of users, a subset of users with highest utility scores, and receives user information from each of the selected users. The system generates the group-activity model based on the user information received from the selected users.

摘要翻译： 一个高性能的活动建模系统使用来自群体组的最佳用户子集的信息为群体组生成群体活动模型。 在操作期间，系统基于效用评分函数计算一组用户的效用评分，使得相应的效用评分指示收集相应用户的上下文信息的有用性或惩罚。 然后，系统从用户组中选择具有最高实用程度分数的用户的子集，并且从每个所选择的用户接收用户信息。 系统基于从所选用户接收的用户信息生成组活动模型。

公开(公告)号：US20130178500A1

公开(公告)日：2013-07-11

申请号：US13685454

申请日：2012-11-26

申请人： Peng Lu ,  Rui Zhang ,  Wansong Yu ,  Mingjie Zhu ,  Yilang Chen

发明人： Peng Lu ,  Rui Zhang ,  Wansong Yu ,  Mingjie Zhu ,  Yilang Chen

IPC分类号： C07D487/04

CPC分类号： C07D487/04

摘要： Hexahydropyrrolo[3,4-b]pyrrole derivatives, preparation methods and pharmaceutical uses thereof are provided. Specifically, dipeptidyl peptidase IV inhibitors presented by following formula (I) are provided. Such compounds can be used for treating or preventing the diseases associated with dipeptidyl peptidase IV, such as diabetes, obesity and hyperlipemia. The compounds presented by formula (I) and pharmaceutically acceptable salts thereof, a method for preparing a pharmaceutical composition thereof and their uses in the manufacture of medicaments for treating or preventing the disease associated with dipeptidyl peptidase IV are provided.

摘要翻译： 提供了六氢吡咯并[3,4-b]吡咯衍生物，其制备方法和药物用途。 具体地，提供了由下式（I）表示的二肽基肽酶IV抑制剂。 这些化合物可用于治疗或预防与二肽基肽酶IV相关的疾病，如糖尿病，肥胖症和高脂血症。 提供式（I）化合物及其药学上可接受的盐，其药物组合物的制备方法及其在制备用于治疗或预防与二肽基肽酶IV相关的疾病的药物中的用途。

公开(公告)号：US20130013943A1

公开(公告)日：2013-01-10

申请号：US13562626

申请日：2012-07-31

申请人： Wendy A. Belluomini ,  David D. Chambliss ,  Joseph S. Glider ,  Himabindu Pucha ,  Rui Zhang

发明人： Wendy A. Belluomini ,  David D. Chambliss ,  Joseph S. Glider ,  Himabindu Pucha ,  Rui Zhang

IPC分类号： G06F1/32

CPC分类号： G06F1/3209 ,  G06F1/3203

摘要： Embodiments of the invention relate to dynamic power management of storage volumes and disk arrays in a storage subsystem to mitigate loss of performance resulting from the power management. The volumes and arrays are prioritized, and in real-time power is selectively reduced in response to both the prioritization and an energy savings goal. A feedback loop is provided to dynamically measure associated power gain based upon a lowering of power consumption, and device selection may be adjusted based upon received feedback.

摘要翻译： 本发明的实施例涉及存储子系统中的存储卷和磁盘阵列的动态功率管理，以减轻由电源管理产生的性能损失。 音量和阵列被优先考虑，并且实时功率被选择性地降低以响应优先级和节能目标。 提供反馈回路以基于功率消耗的降低来动态地测量相关联的功率增益，并且可以基于接收到的反馈来调整设备选择。