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公开(公告)号:US20130096197A1
公开(公告)日:2013-04-18
申请号:US13711329
申请日:2012-12-11
发明人: Mehar Manku , Ian Osterloh , Pierre Wicker , Rene Braeckman , Paresh Soni
IPC分类号: A61K31/202
CPC分类号: A61K31/232 , A61K31/202 , A61K45/06 , G06F19/00
摘要: In various embodiments, the present invention provides methods of treating and/or preventing cardiovascular-related disease and, in particular, a method of blood lipid therapy comprising administering to a subject in need thereof a pharmaceutical composition comprising eicosapentaenoic acid or a derivative thereof.
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公开(公告)号:US20130017256A1
公开(公告)日:2013-01-17
申请号:US13623450
申请日:2012-09-20
申请人: Mehar Manku , Ian Osterloh , Pierre Wicker , Rene Braeckman , Paresh Soni
发明人: Mehar Manku , Ian Osterloh , Pierre Wicker , Rene Braeckman , Paresh Soni
IPC分类号: A61K31/232 , A61K9/48 , A61P3/06
CPC分类号: A61K31/232 , A61K31/202 , A61K45/06 , G06F19/00
摘要: In various embodiments, the present invention provides methods of treating and/or preventing cardiovascular-related disease and, in particular, a method of blood lipid therapy comprising administering to a subject in need thereof a pharmaceutical composition comprising eicosapentaenoic acid or a derivative thereof.
摘要翻译: 在各种实施方案中,本发明提供了治疗和/或预防心血管相关疾病,特别是血脂治疗方法的方法,其包括向有需要的受试者施用包含二十碳五烯酸或其衍生物的药物组合物。
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公开(公告)号:US08324195B2
公开(公告)日:2012-12-04
申请号:US13349150
申请日:2012-01-12
申请人: Mehar Manku , Ian Osterloh , Pierre Wicker , Rene Braeckman , Paresh Soni
发明人: Mehar Manku , Ian Osterloh , Pierre Wicker , Rene Braeckman , Paresh Soni
CPC分类号: A61K31/232 , A61K31/202 , A61K45/06 , G06F19/00
摘要: In various embodiments, the present invention provides methods of treating and/or preventing cardiovascular-related disease and, in particular, a method of blood lipid therapy comprising administering to a subject in need thereof a pharmaceutical composition comprising eicosapentaenoic acid or a derivative thereof.
摘要翻译: 在各种实施方案中,本发明提供了治疗和/或预防心血管相关疾病,特别是血脂治疗方法的方法,其包括向有需要的受试者施用包含二十碳五烯酸或其衍生物的药物组合物。
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公开(公告)号:US08314086B2
公开(公告)日:2012-11-20
申请号:US13284408
申请日:2011-10-28
申请人: Mehar Manku , Ian Osterloh , Pierre Wicker , Rene Braeckman , Paresh Soni
发明人: Mehar Manku , Ian Osterloh , Pierre Wicker , Rene Braeckman , Paresh Soni
CPC分类号: A61K31/232 , A61K31/202 , A61K45/06 , G06F19/00
摘要: In various embodiments, the present invention provides methods of treating and/or preventing cardiovascular-related disease and, in particular, a method of blood lipid therapy comprising administering to a subject in need thereof a pharmaceutical composition comprising eicosapentaenoic acid or a derivative thereof.
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公开(公告)号:US08293728B2
公开(公告)日:2012-10-23
申请号:US13349153
申请日:2012-01-12
申请人: Mehar Manku , Ian Osterloh , Pierre Wicker , Rene Braeckman , Paresh Soni
发明人: Mehar Manku , Ian Osterloh , Pierre Wicker , Rene Braeckman , Paresh Soni
CPC分类号: A61K31/232 , A61K31/202 , A61K45/06 , G06F19/00
摘要: In various embodiments, the present invention provides methods of treating and/or preventing cardiovascular-related disease and, in particular, a method of blood lipid therapy comprising administering to a subject in need thereof a pharmaceutical composition comprising eicosapentaenoic acid or a derivative thereof.
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公开(公告)号:US20120195963A1
公开(公告)日:2012-08-02
申请号:US13439392
申请日:2012-04-04
申请人: Malcolm Peet , Krishna S. Vaddadi
发明人: Malcolm Peet , Krishna S. Vaddadi
IPC分类号: A61K31/202 , A61P25/00 , A61K31/232 , A61K9/48
CPC分类号: A61K31/232 , A61K31/00 , A61K31/202 , A61K31/22 , A61K31/40 , A61K31/445 , A61K31/495 , A61K31/505 , A61K31/54 , A61K31/55 , A61K31/5513 , A61K2300/00
摘要: A pharmaceutical preparation comprising EPA in an appropriately assimilable form where of all the fatty acids present in the preparation at least 90%, and preferably at least 95%, is in the form of EPA and where less than 5%, and preferably less than 3%, is in the form of DHA is provided.
摘要翻译: 一种药物制剂,其包含适当可同化形式的EPA,其中存在于制剂中的所有脂肪酸的至少90%,优选至少95%为EPA形式,其中小于5%,优选小于3 %,以DHA的形式提供。
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公开(公告)号:US20240148683A1
公开(公告)日:2024-05-09
申请号:US18447880
申请日:2023-08-10
发明人: Mehar Manku , Ian Osterloh , Pierre Wicker , Rene Braeckman , Paresh Soni
IPC分类号: A61K31/202 , A61K9/48 , A61K31/232 , A61K45/06 , A61P3/06 , A61P9/00 , A61P9/04 , A61P9/06 , A61P9/10
CPC分类号: A61K31/202 , A61K9/48 , A61K9/4825 , A61K9/4858 , A61K31/232 , A61K45/06 , A61P3/06 , A61P9/00 , A61P9/04 , A61P9/06 , A61P9/10
摘要: The present invention relates to, inter alia, pharmaceutical compositions comprising a polyunsaturated fatty acid and to methods of using the same to treat or prevent cardiovascular-related diseases.
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公开(公告)号:US11717504B2
公开(公告)日:2023-08-08
申请号:US17126619
申请日:2020-12-18
发明人: Paresh Soni
IPC分类号: A61K31/232 , A61P9/10 , A61K9/00 , A61K31/40 , A61K31/505
CPC分类号: A61K31/232 , A61K9/0053 , A61P9/10 , A61K31/40 , A61K31/505
摘要: In various embodiments, the present disclosure provides methods reducing the risk of cardiovascular events in a subject on statin therapy by administering to the subject a pharmaceutical composition comprising about 1 g to about 4 g of eicosapentaenoic acid ethyl ester or a derivative thereof.
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公开(公告)号:US20220323394A1
公开(公告)日:2022-10-13
申请号:US17673061
申请日:2022-02-16
发明人: Ian Osterloh , Pierre Wicker , Rene Braeckman , Paresh Soni , Mehar Manku
IPC分类号: A61K31/232 , G01N33/92 , G01N33/96
摘要: In various embodiments, the present invention provides compositions and methods for treating and/or preventing cardiovascular-related diseases in subject in need thereof.
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公开(公告)号:US11439618B2
公开(公告)日:2022-09-13
申请号:US17148449
申请日:2021-01-13
发明人: Ian Osterloh , Pierre Wicker , Rene Braeckman , Paresh Soni , Mehar Manku
IPC分类号: A61K31/202 , A61K31/232 , A61P9/10 , C07C57/03 , A61P3/06 , A61K31/366 , A61K31/40 , A61K31/505 , A61K9/48
摘要: In various embodiments, the present invention provides compositions and methods for treating and/or preventing cardiovascular-related diseases in subject in need thereof.
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